Gunjiganvi Mallikarjun, Rai Siddharth, Awale Rupali Bhalchandra, Mishra Prabhakar, Gurjar Mohan, Gupta Devendra, Singh Ritu
Department of Trauma Surgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Department of Physical Medicine and Rehabilitation, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Indian J Crit Care Med. 2022 Dec;26(12):1267-1274. doi: 10.5005/jp-journals-10071-24370.
Long-lasting physical, cognitive, and mental health sequelae including depression and anxiety are common in intensive care unit (ICU) survivors.
This study was aimed to assess the immediate and medium-term mental health sequelae-depression and anxiety among coronavirus disease-2019 (COVID-19) ICU survivors.
The COVID-19 ICU survivors of a tertiary level ICU were recruited into this study from 1 July 2020 to 31 October 2020. Willing participants were circulated with an electronic questionnaire. It consisted of demographics and questionnaires related to COVID-19 disease, comorbidities, and a patient health questionnaire (PHQ-9) scale for depression, and generalized anxiety disorder (GAD-7) scale for anxiety. Responses were collected at the time of discharge. Follow-up was done at 2 weeks and 6 months.
Among the 133 COVID-19 ICU survivors contacted, 91 survivors submitted the baseline data at the time of discharge. Fourteen and another 11 survivors were lost to follow-up at 2 weeks and at 6 months. The median age was 52.75 and 68.1% ( = 62/91) were male. The median PHQ-9 and GAD-7 scores showed a statistically significant decrease at 2 weeks and a non-significant decrease at 6 months compared to baseline scores. The GAD-7 score was the same or worse between baselines to 2 weeks, but it reduced between baseline to 6 months for all variables and their subgroups.
This study revealed a high prevalence of anxiety and depression in the immediate post-discharge period. These findings suggest the need for better mental rehabilitation strategies to deal with the well-being of critically ill survivors in future pandemics.
Gunjiganvi M, Rai S, Awale RB, Mishra P, Gurjar M, Gupta D, . Depression and Anxiety among COVID-19 Indian Intensive Care Unit Survivors: A Prospective Observational Study. Indian J Crit Care Med 2022;26(12):1267-1274.
包括抑郁和焦虑在内的长期身体、认知和心理健康后遗症在重症监护病房(ICU)幸存者中很常见。
本研究旨在评估2019冠状病毒病(COVID-19)ICU幸存者的即时和中期心理健康后遗症——抑郁和焦虑。
2020年7月1日至2020年10月31日,将一家三级ICU的COVID-19 ICU幸存者纳入本研究。向愿意参与的人员发放电子问卷。问卷包括人口统计学信息以及与COVID-19疾病、合并症相关的问卷,还有用于评估抑郁的患者健康问卷(PHQ-9)量表和用于评估焦虑的广泛性焦虑障碍(GAD-7)量表。在出院时收集回复。在2周和6个月时进行随访。
在联系的133名COVID-19 ICU幸存者中,91名幸存者在出院时提交了基线数据。14名和另外11名幸存者在2周和6个月时失访。中位年龄为52.75岁,68.1%(n = 62/91)为男性。与基线分数相比,PHQ-9和GAD-7的中位分数在2周时显示出统计学上的显著下降,在6个月时下降不显著。从基线到2周,GAD-7分数相同或更差,但从基线到6个月,所有变量及其亚组的分数均有所降低。
本研究显示出院后即刻焦虑和抑郁的患病率很高。这些发现表明,未来大流行期间需要更好的心理康复策略来应对重症幸存者的健康问题。
Gunjiganvi M, Rai S, Awale RB, Mishra P, Gurjar M, Gupta D, 。COVID-19印度重症监护病房幸存者的抑郁和焦虑:一项前瞻性观察研究。《印度重症监护医学杂志》2022;26(12):1267 - 1274。