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2020 年 2 月 12 日至 3 月 16 日,美国 2019 冠状病毒病(COVID-19)患者的严重结局。

Severe Outcomes Among Patients with Coronavirus Disease 2019 (COVID-19) - United States, February 12-March 16, 2020.

出版信息

MMWR Morb Mortal Wkly Rep. 2020 Mar 27;69(12):343-346. doi: 10.15585/mmwr.mm6912e2.

Abstract

Globally, approximately 170,000 confirmed cases of coronavirus disease 2019 (COVID-19) caused by the 2019 novel coronavirus (SARS-CoV-2) have been reported, including an estimated 7,000 deaths in approximately 150 countries (1). On March 11, 2020, the World Health Organization declared the COVID-19 outbreak a pandemic (2). Data from China have indicated that older adults, particularly those with serious underlying health conditions, are at higher risk for severe COVID-19-associated illness and death than are younger persons (3). Although the majority of reported COVID-19 cases in China were mild (81%), approximately 80% of deaths occurred among adults aged ≥60 years; only one (0.1%) death occurred in a person aged ≤19 years (3). In this report, COVID-19 cases in the United States that occurred during February 12-March 16, 2020 and severity of disease (hospitalization, admission to intensive care unit [ICU], and death) were analyzed by age group. As of March 16, a total of 4,226 COVID-19 cases in the United States had been reported to CDC, with multiple cases reported among older adults living in long-term care facilities (4). Overall, 31% of cases, 45% of hospitalizations, 53% of ICU admissions, and 80% of deaths associated with COVID-19 were among adults aged ≥65 years with the highest percentage of severe outcomes among persons aged ≥85 years. In contrast, no ICU admissions or deaths were reported among persons aged ≤19 years. Similar to reports from other countries, this finding suggests that the risk for serious disease and death from COVID-19 is higher in older age groups.

摘要

据报道,全球范围内已确诊约 17 万例 2019 年新型冠状病毒(SARS-CoV-2)引起的 2019 冠状病毒病(COVID-19)病例,在约 150 个国家中,估计有 7000 人死亡(1)。2020 年 3 月 11 日,世界卫生组织宣布 COVID-19 疫情为大流行(2)。中国的数据表明,老年人,尤其是患有严重基础疾病的老年人,患严重 COVID-19 相关疾病和死亡的风险高于年轻人(3)。尽管中国报告的 COVID-19 病例大多数为轻症(81%),但约 80%的死亡发生在年龄≥60 岁的成年人中;仅有 1 例(0.1%)死亡发生在年龄≤19 岁的人(3)。本报告分析了 2020 年 2 月 12 日至 3 月 16 日期间美国发生的 COVID-19 病例以及疾病严重程度(住院、入住重症监护病房[ICU]和死亡)按年龄组分布情况。截至 3 月 16 日,美国向疾病预防控制中心报告了总计 4226 例 COVID-19 病例,其中多名老年人在长期护理机构居住时感染(4)。总体而言,31%的病例、45%的住院、53%的 ICU 入住和 80%的 COVID-19 死亡发生在年龄≥65 岁的成年人中,≥85 岁人群的严重后果比例最高。相比之下,年龄≤19 岁的人没有 ICU 入住或死亡报告。与其他国家的报告相似,这一发现表明,COVID-19 导致严重疾病和死亡的风险在年龄较大的人群中更高。

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