Alcalay M, Goupy M C, Azais I, Bontoux D
Department of Rheumatology, Centre Hospitalier et Universitaire de Poitiers, France.
Arthritis Rheum. 1987 Oct;30(10):1182-6. doi: 10.1002/art.1780301016.
Since 1984, there have been several reports of a destructive spondylarthropathy occurring in patients who have received hemodialysis over a long period of time. Two cases of a similar syndrome were observed in nonhemodialyzed patients with chronic renal failure, one of whom underwent a lumbar disc excision. The results of disc examination and of radiographic and biologic investigations prompted reconsideration of factors previously considered to be pathogenetic (amyloidosis, hydroxyapatite crystal deposition, aluminum toxicity), except one: secondary hyperparathyroidism.
自1984年以来，有几篇报告称，长期接受血液透析的患者会出现一种破坏性脊椎关节病。在未接受血液透析的慢性肾衰竭患者中观察到两例类似综合征的病例，其中一例接受了腰椎间盘切除术。椎间盘检查以及影像学和生物学检查结果促使人们重新审视先前被认为是致病因素的因素（淀粉样变性、羟基磷灰石晶体沉积、铝中毒），但有一种因素除外：继发性甲状旁腺功能亢进。
