Kuntz D, Naveau B, Bardin T, Drueke T, Treves R, Dryll A
Arthritis Rheum. 1984 Apr;27(4):369-75. doi: 10.1002/art.1780270402.
Spinal radiologic lesions suggestive of destructive spondylarthropathy were found in 10 patients on long-term hemodialysis. These lesions were characterized by severe narrowing of the intervertebral disc, associated with erosions and geodes of the adjacent vertebral plates without osteophytosis. In 9 of the 10 patients the lesions were located in the cervical spine, and in 1 patient, in the lumbar spine. Microbial spondylitis, degenerative disc disease, and destructive spondylarthropathy of calcium pyrophosphate dihydrate deposition disease were each, in turn, ruled out. The finding of apatite crystals by transmission electron microscopy in 1 disc specimen suggests that these crystals may be associated with destructive vertebral disc lesions in dialysis patients.
在10例长期血液透析患者中发现了提示破坏性脊椎关节病的脊柱放射学病变。这些病变的特征是椎间盘严重狭窄，伴有相邻椎体板的侵蚀和骨突，无骨赘形成。10例患者中有9例病变位于颈椎，1例位于腰椎。依次排除了微生物性脊柱炎、退行性椎间盘疾病和焦磷酸钙二水合物沉积病的破坏性脊椎关节病。在1个椎间盘标本中通过透射电子显微镜发现磷灰石晶体，提示这些晶体可能与透析患者的椎间盘破坏性病变有关。
