[一例成人头颈部原发性软组织肉瘤的病例报告]
[A case report of adult primary soft tissue sarcoma of the head and neck].
作者信息
Liu Leifeng, Qiu Haitao, Hui Minglang, Jiang Feng, Wang Daihong, Lin Yuying, Yang Xinjian, Yao Jun
机构信息
Department of Otolaryngology Head and Neck Surgery，Affiliated Hospital of Guangdong Medical University，Zhanjiang，524000，China.
Graduate School of Guangdong Medical University.
出版信息
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2023 Feb;37(2):146-149. doi: 10.13201/j.issn.2096-7993.2023.02.015.
Head and neck primary soft tissue sarcoma is a rare adult connective tissue malignant tumor derived from mesenchymal tissue, which can occur in the paranasal sinuses, throat or neck space.The clinical manifestations are local spread masses in the head and neck or difficulty breathing, swallowing, etc al. MRI and enhanced CT examination are the most commonly used to diagnose such diseases. Pathological diagnosis requires immunohistochemistry combined with FISH to detect MDM2 and CDK4. In this report，two cases of primary soft tissue sarcoma were reported,one is parotid high-differentiated liposarcoma and the other is laryngeal dedifferentiated leiomyosarcoma, introducing the characteristics diagnosis and treatment, and reviewing the relevant literature.
头颈部原发性软组织肉瘤是一种罕见的源自间叶组织的成人结缔组织恶性肿瘤，可发生于鼻窦、咽喉或颈部间隙。临床表现为头颈部局部扩散性肿块或呼吸困难、吞咽困难等。MRI和增强CT检查是诊断此类疾病最常用的方法。病理诊断需要免疫组织化学结合FISH检测MDM2和CDK4。本报告报道了2例原发性软组织肉瘤病例，1例为腮腺高分化脂肪肉瘤，另1例为喉去分化平滑肌肉瘤，介绍了其诊断和治疗特点，并复习了相关文献。
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