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Hazardous Drug Exposure: Case Report Analysis From a Prospective, Multisite Study of Oncology Nurses' Exposure in Ambulatory Settings.危险药物暴露:一项前瞻性、多地点研究中肿瘤科护士在门诊环境中暴露情况的病例报告分析。
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Application of an innovative high-throughput liquid chromatography-tandem mass spectrometry method for simultaneous analysis of 18 hazardous drugs to rule out accidental acute chemotherapy exposures in health care workers.应用创新的高通量液相色谱-串联质谱法同时分析18种危险药物,以排除医护人员意外急性化疗暴露情况。
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An intervention to evaluate & improve handling of cancer drugs in a tertiary care hospital in India.在印度一家三级护理医院进行的一项评估并改善癌症药物处理情况的干预措施。
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临床护士抗肿瘤药物安全操作培训对认知、依从性和压力处理的影响。

Effects of safe handling education on cognition, compliance and stress handling of antineoplastic drugs in clinical nurses.

机构信息

Department of Nursing, Pai Chai University, Daejeon, South Korea.

Department of Nursing, Dongseo University, Busan, South Korea.

出版信息

Nurs Open. 2023 Jun;10(6):4144-4152. doi: 10.1002/nop2.1626. Epub 2023 Feb 9.

DOI:10.1002/nop2.1626
PMID:36757101
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10170956/
Abstract

To evaluate the effects of safe-handling education on the cognition, practice and stress handling of antineoplastic drugs in clinical nurses. This study uses a quasi-experimental, non-equivalent control group pre-test and post-test design. The experimental and control groups had 30 nurses each, who handled antineoplastic drugs from three institutions. This study examines the safe handling of antineoplastic drugs six times, for two hours each over two weeks. To verify the homogeneity of the experimental and control groups and the effectiveness of safe-handling education about antineoplastic drugs, a chi-square test and independent samples t-test were performed. The results were statistically significant in both groups (cognition [t = 6.84, p < 0.001], practice [t = 5.86, p < 0.001], and the stress of handling antineoplastic drugs [t = 5.15, p < 0.001]). Education on ways to safely handle antineoplastic drugs improves cognition, practice and stress handling of these drugs; moreover, proper education minimizes exposure.

摘要

目的

评价安全处理教育对临床护士对抗肿瘤药物的认知、实践和压力处理的影响。本研究采用准实验、非等组前后测设计。实验组和对照组各 30 名护士,来自三个机构,处理抗肿瘤药物。研究共进行六次抗肿瘤药物安全处理,每周两次,每次两小时。为了验证实验组和对照组的同质性和抗肿瘤药物安全处理教育的有效性,进行了卡方检验和独立样本 t 检验。两组的结果均具有统计学意义(认知 [t=6.84,p<0.001]、实践 [t=5.86,p<0.001] 和处理抗肿瘤药物的压力 [t=5.15,p<0.001])。抗肿瘤药物安全处理教育可提高认知、实践和处理这些药物的压力;此外,适当的教育可最大限度地减少接触。