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纤维肌痛的非药物疗法:医生的新视野,患者的新希望。

Non-pharmacological therapies in Fibromyalgia: New horizons for physicians, new hopes for patients.

作者信息

Majdoub Fatma, Ben Nessib Dorra, Ferjani Hanene Lassoued, Kaffel Dhia, Triki Wafa, Maatallah Kaouther, Hamdi Wafa

机构信息

Rheumatology Department, Kassab Orthopedics Institute, Tunis, Tunisia.

Faculty of Medicine of Tunis, University Tunis El Manar, Tunis, Tunisia.

出版信息

Musculoskeletal Care. 2023 Feb 9. doi: 10.1002/msc.1741.

Abstract

INTRODUCTION

Fibromyalgia (FM) is a chronic musculoskeletal condition characterised by reduced quality of life and severe limitations in daily living activities. Considering the wide spectrum of symptoms and the ineffectiveness of a single pharmacological approach, the latest clinical guidelines recommend non-pharmacological therapies as both an alternative and a better-tolerated approach. Several studies have been conducted to determine the effectiveness of non-pharmacological therapies in the management of FM.

AIMS

Through a literature review, this paper aims to describe the different complementary therapies and investigate their potential sustainability and effectiveness on FM symptoms in the short and/or long term.

METHODS

We searched the PubMed and Google Scholar databases using broad search terms up to June 2022, to identify all types of study designs restricted to human subjects on non-pharmacological therapies in FM.

RESULTS

Recent evidence demonstrated that physical activity is the mainstay of therapeutic management, highlighting the relevance of walking as the best method of exercise in FM patients. Nevertheless, adherence to physical activity remains fraught with obstacles that could be overcome with a multimodal and multidisciplinary approach involving a wide range of passive therapies. The effectiveness of passive non-pharmacological therapies remains however unproven in the long term. They can be therefore suggested as 'adjunct' or 'bridge' therapy to improve adherence to physical activity.

CONCLUSION

To conclude, FM management requires a multimodal and symptom-based approach, guided by the predominant bothersome symptom on the one hand, and the preferences of each patient on the other hand.

摘要

引言

纤维肌痛(FM)是一种慢性肌肉骨骼疾病,其特征是生活质量下降和日常生活活动严重受限。鉴于症状范围广泛且单一药物治疗方法无效,最新临床指南推荐非药物治疗作为一种替代方法且耐受性更好。已经开展了多项研究来确定非药物治疗在纤维肌痛管理中的有效性。

目的

通过文献综述,本文旨在描述不同的补充疗法,并研究它们在短期和/或长期对纤维肌痛症状的潜在可持续性和有效性。

方法

我们在PubMed和谷歌学术数据库中进行检索,使用宽泛的检索词截至2022年6月,以识别所有限于人类受试者的关于纤维肌痛非药物治疗的研究设计类型。

结果

最近的证据表明,身体活动是治疗管理的主要支柱,突出了步行作为纤维肌痛患者最佳运动方式的相关性。然而,坚持身体活动仍然充满障碍,而采用包括多种被动疗法的多模式和多学科方法可以克服这些障碍。然而,被动非药物治疗的长期有效性尚未得到证实。因此,可以将它们作为“辅助”或“过渡”疗法来提高对身体活动的依从性。

结论

总之,纤维肌痛的管理需要一种多模式且基于症状的方法,一方面以最主要的困扰症状为指导,另一方面以每个患者的偏好为指导。

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