Hörster W, Ettlinger G
University of Bielefeld, F.R.G.
Behav Brain Res. 1987 Oct;26(1):1-17. doi: 10.1016/0166-4328(87)90011-8.
Unilateral removals of the posterior insula or of the second somatic sensory projection area (SII) were made in respectively 8 and 6 monkeys. These animals were divided into a 'contralateral' group of 7 with removals from the hemisphere opposite to the preferred hand; and an 'ipsilateral' group of 7 animals with removals from the hemisphere on the same side as the preferred hand. In addition, 6 unoperated monkeys were trained comparably. Both the contralateral and ipsilateral animals were impaired in comparison with unoperated animals at threshold discriminations of graded roughness and/or sizes when using the hand opposite the removals. Animals with contralateral ablations were impaired in comparison with those having ipsilateral ablations only in a few of many instances: with the hand ipsilateral to the removals at re-learning a tactile discrimination and at learning an auditory discrimination; with the hand opposite to the removals when it was initially used on visual or auditory tasks that had already been mastered with the other hand. It is suggested that in addition to SII the insula is also organized asymmetrically in relation to hand preference in the monkey, but the insula of the predominant hemisphere may be involved as much in non-tactual as tactual performances, for example in tasks involving successive discrimination and when a familiar task has to be performed initially with the other hand.
分别对8只猴子进行了后岛叶的单侧切除，对6只猴子进行了第二躯体感觉投射区（SII）的单侧切除。这些动物被分为“对侧”组7只，切除的是与优势手相对的半球；以及“同侧”组7只，切除的是与优势手同侧的半球。此外，对6只未做手术的猴子进行了类似的训练。与未做手术的动物相比，对侧和同侧的动物在使用与切除部位相对的手进行分级粗糙度和/或大小的阈值辨别时均受损。在许多情况下，只有少数情况是对侧切除的动物与同侧切除的动物相比受损：在重新学习触觉辨别和学习听觉辨别时，使用与切除部位同侧的手；在最初使用与已用另一只手掌握的视觉或听觉任务相对的手时。研究表明，除了SII之外，猴子的岛叶在与手偏好的关系上也呈不对称组织，但优势半球的岛叶在非触觉表现和触觉表现中可能都有涉及，例如在涉及连续辨别的任务中，以及当必须先用另一只手执行熟悉的任务时。
