College of Earth and Environmental Sciences, University of the Punjab, Lahore, Pakistan.
Department of Environmental Science and Policy, Faculty of Basic Sciences, Lahore School of Economics, Lahore, Pakistan.
Sci Total Environ. 2023 May 1;871:162084. doi: 10.1016/j.scitotenv.2023.162084. Epub 2023 Feb 8.
The present study was conducted to evaluate Carcinogenic (TR) and non-carcinogenic (THQ) human health risk of organochlorine pesticides (OCPs) in three edible fish species (Labeo boga, Channa marulius and Wallago attu) of River Chenab, Pakistan using USEPA human health risk assessment model. Holistic GIS (Geographic information system) based Geo-Statistical approach has been employed for the first time in River Chenab, Pakistan to categorize contaminated risk zones of OCPs based on single pollution index. The ∑OCPs concentrations in fish species were ranged from 5.09 to 414 ng/g with the prevalence of dieldrin. Results of single pollution index of DDE, aldrin, dieldrin and ∑endosulfan revealed River Chenab as polluted and risk zone area. Distribution pattern assessed significantly higher (p < 0.05) concentrations of OCPs in downstream area suggesting substantial pollution of surrounded industrial region. The human health risk assessment depicted no harmful non-carcinogenic (THQ) risk except for ΣOCPs concentration of C. marulius. Significant carcinogenic (TR) health risk exhibited by all examined OCPs from maximum of the studied sites. Therefore, the high carcinogenic human health risk had highlighted an immediate removal of continuous disposal of OCPs in the River Chenab.
本研究旨在利用美国环保署人类健康风险评估模型，评估巴基斯坦 Chenab 河三种食用鱼类（Labeo boga、Channa marulius 和 Wallago attu）中有机氯农药（OCPs）的致癌（TR）和非致癌（THQ）人类健康风险。本研究首次在巴基斯坦 Chenab 河采用基于整体 GIS（地理信息系统）的地质统计方法，根据单一污染指数对 OCPs 的污染风险区进行分类。鱼类中∑OCPs 浓度范围为 5.09-414ng/g，以狄氏剂为主。DDE、艾氏剂、狄氏剂和∑硫丹的单一污染指数结果表明 Chenab 河受到污染，存在风险区。分布模式评估显示下游地区 OCPs 浓度显著较高（p<0.05），表明周边工业区域受到严重污染。人类健康风险评估表明，除 C. marulius 的∑OCPs 浓度外，无有害的非致癌（THQ）风险。所有检测到的 OCPs 均显示出显著的致癌（TR）健康风险，这表明研究地点中存在高致癌的人类健康风险，因此急需清除 Chenab 河中持续排放的 OCPs。
