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新冠病毒肺炎患者的焦虑和创伤后应激障碍发生率较高:一项前瞻性对比研究。

Higher anxiety and perceived trauma among COVID-19 patients: a prospective comparative study.

机构信息

School of Medicine, Iran University of Medical Science, Tehran, Iran.

Department of Psychiatry, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

出版信息

BMC Psychiatry. 2023 Feb 9;23(1):100. doi: 10.1186/s12888-023-04574-6.

Abstract

BACKGROUND AND PURPOSE

Psychiatric disorders such as anxiety, depression, and traumatic stress are not rare during infectious outbreaks, as the COVID-19 pandemic has posed a great concern to the general population. In this study, we aimed to investigate whether experiencing psychiatric symptoms during COVID-19 is the result of the burden of carrying an illness or the COVID-19 itself.

METHOD

Two hundred ten subjects and three different groups of participants (COVID-19 patients, university staff, and orthopedic patients) were recruited. They answered a demographic questionnaire, Yale-Brown Obsessive-Compulsive Scale (YBOCS) test for OCD symptoms, Impact of Event Scale-Revised (IES-R) for perceived trauma, Beck Anxiety Inventory (BAI) for anxiety, and Beck Depression Inventory (BDI) for depression assessments using phone or face-to-face interviews.

RESULT

At least one OCD symptom was observed in 85.7% of the subjects. However, there was no significant difference between the 3 groups (p = 0.2194). Perceived trauma was significantly higher among COVID-19 patients followed by university staff and orthopedic patients (23.73, 16.21, 11.51 mean IES-R scores respectively, p = 8.449e). COVID-19 patients also showed higher anxiety (mean BAI score: 17.00) than the university staff and orthopedic patients' group (9.22 and 5.56 respectively) (p = 6.175e). BDI score did not show much variation for depression, the mean score was 9.66, 9.49, and 6.7 for the COVID-19 patients, university staff, and orthopedic patients respectively, (p = 0.2735).

CONCLUSION

Perceived trauma and anxiety symptoms are significantly higher in COVID-19 patients and the symptoms of OCD and depression do not differ between COVID-19 and non-COVID-19 people, so the necessity of screening and following treatment of patients with COVID-19 should be kept in mind.

TRIAL REGISTRATION

IR.IUMS.FMD.REC.1399.761.

摘要

背景与目的

在传染病爆发期间,焦虑、抑郁和创伤后应激等精神障碍并不罕见,因为 COVID-19 大流行引起了公众的极大关注。在这项研究中,我们旨在探讨在 COVID-19 期间经历精神症状是疾病负担的结果还是 COVID-19 本身的结果。

方法

招募了 210 名受试者和三组不同的参与者(COVID-19 患者、大学教职员工和骨科患者)。他们通过电话或面对面访谈回答了人口统计学问卷、耶鲁-布朗强迫症量表(YBOCS)测试强迫症症状、修订后的事件影响量表(IES-R)评估感知创伤、贝克焦虑量表(BAI)评估焦虑和贝克抑郁量表(BDI)评估抑郁。

结果

至少有 85.7%的受试者出现了至少一种强迫症症状。然而,三组之间没有显著差异(p=0.2194)。COVID-19 患者的感知创伤明显更高,其次是大学教职员工和骨科患者(23.73、16.21、11.51 的平均 IES-R 评分,p=8.449e)。COVID-19 患者的焦虑程度也高于大学教职员工和骨科患者组(平均 BAI 评分:17.00)(p=6.175e)。BDI 评分对抑郁的变化不大,COVID-19 患者、大学教职员工和骨科患者的平均评分分别为 9.66、9.49 和 6.7(p=0.2735)。

结论

COVID-19 患者的感知创伤和焦虑症状明显更高,而 COVID-19 和非 COVID-19 人群的强迫症和抑郁症状没有差异,因此应牢记对 COVID-19 患者进行筛查和后续治疗的必要性。

试验注册

IR.IUMS.FMD.REC.1399.761。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da44/9909932/41dd60acf940/12888_2023_4574_Fig1_HTML.jpg

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