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由两颗轴向种植体和两颗倾斜种植体支持的全牙弓即刻固定修复体的临床疗效:一项随访12至15年的回顾性队列研究。

Clinical outcomes of full-arch immediate fixed prostheses supported by two axial and two tilted implants: A retrospective cohort study with 12-15 years of follow-up.

作者信息

Agliardi Enrico Luigi, Pozzi Alessandro, Romeo Davide, Del Fabbro Massimo

机构信息

Advanced Oral Surgery Unit, Department of Dentistry, Vita Salute University, San Raffaele Hospital, Milan, Italy.

Dental College of Georgia, Augusta, USA.

出版信息

Clin Oral Implants Res. 2023 Apr;34(4):351-366. doi: 10.1111/clr.14047. Epub 2023 Feb 22.

Abstract

PURPOSE

To retrospectively assess clinical and radiographic outcomes of immediately loaded full-arch fixed prostheses supported by axial and tilted implants up to 15 years of function.

MATERIALS AND METHODS

Patients with one completely edentulous arch received an immediate full-arch fixed prosthesis supported by two anterior axial and two posterior tilted implants. Definitive prosthesis consisting of a CAD-CAM titanium framework and acrylic teeth was delivered 6 months later. Patients were regularly followed to assess clinical parameters and marginal bone level (MBL) change. Multilevel regression analysis was performed to investigate factors affecting implant failure and MBL.

RESULTS

Six hundred ninety-two implants were placed in 72 maxillae and 101 mandibles. Seven maxillary implants (5 axial and 2 tilted) in 6 patients and 12 mandibular implants (6 axial and 6 tilted) in 5 patients failed. 15-year cumulative implant survival was 97.51% and 96.91% in maxilla and mandible, respectively (p = .64). After 10 years, the difference in MBL between axial and tilted implants was not significant in the maxilla (p = .47, 65 patients), while it was in the mandible (p < .001, 80 patients). Significant higher bone loss was reported in the mandible at both 5- and 10-year follow-up (p < .001 and p = .004, respectively). Mixed-effect multilevel linear regression evidenced a correlation between arch and bone loss at 5- and 10-year follow-up, while no correlation was found with age, gender, smoking, diabetes, and history of periodontal disease.

CONCLUSION

This long-term study suggests that the present technique can be considered a viable treatment modality for the immediate rehabilitation of both maxilla and mandible.

摘要

目的

回顾性评估由轴向种植体和倾斜种植体支持的即刻负重全牙弓固定修复体长达15年的临床和影像学结果。

材料与方法

单颌全牙列缺失患者接受由两颗前牙区轴向种植体和两颗后牙区倾斜种植体支持的即刻全牙弓固定修复体。6个月后交付由计算机辅助设计与制造(CAD-CAM)钛支架和丙烯酸树脂牙组成的最终修复体。定期随访患者以评估临床参数和边缘骨水平(MBL)变化。进行多水平回归分析以研究影响种植体失败和MBL的因素。

结果

共在72例上颌骨和101例下颌骨中植入692颗种植体。6例患者的7颗上颌种植体(5颗轴向种植体和2颗倾斜种植体)和5例患者的12颗下颌种植体(6颗轴向种植体和6颗倾斜种植体)失败。上颌和下颌种植体的15年累计存留率分别为97.51%和96.91%(p = 0.64)。10年后,上颌骨中轴向种植体和倾斜种植体之间的MBL差异不显著(p = 0.47,65例患者),而下颌骨中差异显著(p < 0.001,80例患者)。在5年和10年随访时,下颌骨的骨吸收均显著更高(分别为p < 0.001和p = 0.004)。混合效应多水平线性回归表明在5年和10年随访时牙弓与骨吸收之间存在相关性,而未发现与年龄、性别、吸烟、糖尿病和牙周病病史相关。

结论

这项长期研究表明,目前的技术可被视为上颌骨和下颌骨即刻修复的一种可行治疗方式。

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