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轴向种植体与倾斜种植体周围边缘骨的转归:一项系统评价

The fate of marginal bone around axial vs. tilted implants: a systematic review.

作者信息

Del Fabbro Massimo, Ceresoli Valentina

出版信息

Eur J Oral Implantol. 2014 Summer;7 Suppl 2:S171-89.

Abstract

AIMS

The use of tilted implants has recently gained popularity as a feasible option for the treatment of edentulous jaws by means of implant-supported rehabilitations without recurring to grafting procedures. The aim of this review was to compare the crestal bone level change around axially placed vs. tilted implants supporting fixed prosthetic reconstructions for the rehabilitation of partially and fully edentulous jaws, after at least 1 year of function.

MATERIALS AND METHODS

An electronic search of databases plus a hand search on the most relevant journals up to January 2014 was performed. The articles were selected using specific inclusion criteria, independent of the study design. Data on marginal bone loss and implant survival were extracted from included articles and statistically analysed to investigate the effect of implant tilting, location, prosthesis type, loading mode and study design. The difference in crestal bone level change around axial vs. tilted implants was analysed using meta-analysis.

RESULTS

The literature search yielded 758 articles. A first screening based on titles and abstracts identified 62 eligible studies. After a full-text review, 19 articles (14 prospective and five retrospective studies) were selected for analysis. A total of 670 patients have been rehabilitated with 716 prostheses (415 in the maxilla, 301 in the mandible), supported by a total of 1494 axial and 1338 tilted implants. Periimplant crestal bone loss after 1 year of function ranged from 0.43 to 1.13 mm for axial implants and from 0.34 to 1.14 mm for tilted implants. In spite of a trend for a lower bone loss around axial implants with respect to tilted ones at 12 months, as well as after 3 or more years of function, no significant difference could be found (P = 0.09 and P = 0.30, respectively). The location (maxilla vs. mandible), the loading mode (immediate vs. delayed), the restoration type (full vs. partial prosthesis) and the study design (prospective vs. retrospective) had no significant effect on marginal bone loss. Forty-six implants (18 axial and 28 tilted) failed in 38 patients within the first year of function. All failures except five occurred in the maxilla. After 12 months of loading, the survival rate of implants placed in the maxilla (97.4%) was significantly lower as compared to the mandible (99.6%). No prosthesis failure was reported.

CONCLUSIONS

Tilting of the implants does not induce significant alteration in crestal bone level change as compared to conventional axial placement after 1 year of function. The trend seems to be unchanged over time even though the amount of long-term data is still scarce. The use of tilted implants to support fixed partial and full-arch prostheses for the rehabilitation of edentulous jaws can be considered a predictable technique, with an excellent prognosis in the short and mid-term. Further long-term trials, possibly randomised, are needed to determine the efficacy of this surgical approach and the remodelling pattern of marginal bone in the long term.

摘要

目的

倾斜种植体的应用近来颇受关注,它为无牙颌的种植支持修复治疗提供了一种可行的选择,无需进行植骨手术。本综述的目的是比较轴向种植体与倾斜种植体在支持固定修复重建部分或全口无牙颌功能至少1年后,其种植体周围嵴顶骨水平的变化。

材料与方法

对数据库进行电子检索,并对截至2014年1月的最相关期刊进行手工检索。文章根据特定的纳入标准进行选择,与研究设计无关。从纳入的文章中提取边缘骨丢失和种植体存留的数据,并进行统计学分析,以研究种植体倾斜、位置、修复体类型、加载方式和研究设计的影响。使用荟萃分析比较轴向种植体与倾斜种植体周围嵴顶骨水平变化的差异。

结果

文献检索共获得758篇文章。基于标题和摘要的初步筛选确定了62项符合条件的研究。经过全文审查,选择了19篇文章(14项前瞻性研究和5项回顾性研究)进行分析。共有670例患者接受了716个修复体的修复(上颌415个,下颌301个),共使用了1494个轴向种植体和1338个倾斜种植体。轴向种植体在功能1年后的种植体周围嵴顶骨丢失范围为0.43至1.13mm,倾斜种植体为0.34至1.14mm。尽管在12个月时以及功能3年或更长时间后,轴向种植体周围骨丢失有低于倾斜种植体的趋势,但未发现显著差异(P分别为0.09和0.30)。种植体位置(上颌与下颌)、加载方式(即刻与延迟)、修复类型(全口与部分修复体)和研究设计(前瞻性与回顾性)对边缘骨丢失均无显著影响。在功能的第一年,38例患者中有46个种植体(18个轴向和28个倾斜)失败。除5例之外,所有失败均发生在上颌。加载12个月后,上颌种植体的存留率(97.4%)显著低于下颌(99.6%)。未报告修复体失败。

结论

与传统轴向种植体植入1年后相比,种植体倾斜不会导致嵴顶骨水平变化的显著改变。尽管长期数据仍然稀少,但随着时间推移这种趋势似乎不变。使用倾斜种植体支持固定局部和全牙弓修复体来修复无牙颌可被认为是一种可预测的技术,在短期和中期预后良好。需要进一步的长期试验,可能是随机试验,以确定这种手术方法的长期疗效以及边缘骨的重塑模式。

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