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铜催化的Sonogashira反应：2014年以来的进展与展望

Copper-catalyzed Sonogashira reactions: advances and perspectives since 2014.

作者信息

Arundhathi Koduvarathodi Vadakkethil, Vaishnavi Palemkunnummal, Aneeja Thaipparambil, Anilkumar Gopinathan

机构信息

School of Chemical Sciences, Mahatma Gandhi University Priyadarsini Hills P.O Kottayam Kerala 686560 India

出版信息

RSC Adv. 2023 Feb 7;13(7):4823-4834. doi: 10.1039/d2ra07685c. eCollection 2023 Jan 31.

DOI:10.1039/d2ra07685c
PMID:36760276
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9903355/
Abstract

Transition metal catalyzed Sonogashira coupling reaction has evolved as an efficient pathway for the construction of C-C bonds. Initially, palladium cooperating with copper was considered as the efficient catalytic system for this reaction. However, nowadays there have been astonishing progress in copper catalyzed Sonogashira coupling reactions. Copper catalyzed reactions have attained significant attention owing to the cost effective and environmentally benign characteristics of this metal compared to palladium. This review summarizes the recent developments in copper catalyzed Sonogashira coupling covering literature from 2014 to 2021.

摘要

过渡金属催化的Sonogashira偶联反应已发展成为构建碳-碳键的有效途径。最初，钯与铜协同作用被认为是该反应的有效催化体系。然而，如今铜催化的Sonogashira偶联反应已取得了惊人的进展。与钯相比，铜催化的反应因其成本效益高和环境友好的特性而备受关注。本综述总结了2014年至2021年期间铜催化的Sonogashira偶联反应的最新进展。

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