Koblick Sarah B, Yu Miao, DeMoss Matthew, Liu Qiaoxue, Nessle Charles N, Rozwadowski Michelle, Troost Jonathan P, Miner Jennifer A, Hassett Afton, Carlozzi Noelle E, Barton Debra L, Tewari Muneesh, Hanauer David A, Choi Sung Won
Department of Pediatrics, University of Michigan, Ann Arbor, MI, USA.
Michigan Institute for Clinical and Health Research, University of Michigan, Ann Arbor, MI, USA.
Mhealth. 2023 Jan 28;9:5. doi: 10.21037/mhealth-22-24. eCollection 2023.
The Roadmap mobile health (mHealth) app was developed to provide health-related quality of life (HRQOL) support for family caregivers of patients with cancer.
Eligibility included: family caregivers (age ≥18 years) who self-reported as the primary caregiver of their pediatric patient with cancer; patients (age ≥5 years) who were receiving cancer care at the University of Michigan. Feasibility was calculated as the percentage of caregivers who logged into and engaged with it at least twice weekly for at least 50% of the 120-day study duration. Feasibility and acceptability was also assessed through a Feasibility and Acceptability questionnaire and the Mobile App Rating Scale to specifically assess app-quality. Exploratory analyses were also conducted to assess HRQOL self- or parent proxy assessments and physiological data capture.
Between September 2020-September 2021, 100 participants (or 50 caregiver-patient dyads) consented and enrolled in the ONC Roadmap study for 120-days. Feasibility of the study was met, wherein the majority of caregivers (N=32; 65%) logged into ONC Roadmap and engaged with it at least twice weekly for at least 50% of the study duration (defined in the Protocol). The Feasibility and Acceptability questionnaire responses indicated that the study was feasible and acceptable with the majority (>50%) reporting or with positive [( + ) - ( + )] in each of the domains (e.g., Fitbit use, ONC Roadmap use, completing longitudinal assessments, engaging in similar future study, study expectations). Improvements were seen across the majority of the mental HRQOL domains across all groups; even though underpowered, there were significant improvements in caregiver-specific aspects of HRQOL and anxiety and in depression and fatigue for children (ages 8-17 years), and a trend toward improvement in depression for children ages 8-17 years and in fatigue for adult patients.
This study supports that mHealth technology may be a promising platform to provide HRQOL support for caregivers of pediatric patients with cancer. Importantly, the findings suggest that the study protocol was feasible, and participants were favorable to participate in future studies of this intervention alongside routine cancer care delivery.
开发了“路线图”移动健康（mHealth）应用程序，为癌症患者的家庭护理人员提供与健康相关的生活质量（HRQOL）支持。
纳入标准包括：自我报告为其患癌儿科患者主要护理人员的家庭护理人员（年龄≥18岁）；在密歇根大学接受癌症治疗的患者（年龄≥5岁）。可行性计算为在120天研究期间至少50%的时间内每周至少登录并使用该应用程序两次的护理人员的百分比。还通过可行性和可接受性问卷以及移动应用程序评分量表来评估可行性和可接受性，以专门评估应用程序质量。还进行了探索性分析，以评估HRQOL的自我或家长代理评估以及生理数据采集。
在2020年9月至2021年9月期间，100名参与者（或50对护理人员 - 患者二元组）同意并参加了为期120天的ONC路线图研究。该研究的可行性得到满足，其中大多数护理人员（N = 32；65%）登录了ONC路线图，并在至少50%的研究期间每周至少使用两次（如方案中所定义）。可行性和可接受性问卷的回复表明该研究是可行且可接受的，大多数（>50%）在每个领域（如使用Fitbit、使用ONC路线图、完成纵向评估、参与类似的未来研究、研究期望）报告为 或 且为积极的[（ + ） - （ + ）]。在所有组的大多数心理HRQOL领域都有改善；尽管样本量不足，但在护理人员特定的HRQOL方面以及焦虑方面以及8 - 17岁儿童的抑郁和疲劳方面有显著改善，并且8 - 17岁儿童的抑郁和成年患者的疲劳有改善趋势。
本研究支持移动健康技术可能是为患癌儿科患者的护理人员提供HRQOL支持的一个有前景的平台。重要的是，研究结果表明研究方案是可行的，并且参与者愿意在常规癌症护理的同时参与该干预措施的未来研究。
