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因未遵医嘱服用降压药导致的高血压急症和前鼻出血:一例报告

Hypertensive Urgency and Anterior Epistaxis Caused by Antihypertensive Medication Noncompliance: A Case Report.

作者信息

Bereda Gudisa

机构信息

Pharmacy Department, Alert Comprehensive Specialized Hospital, Addis Ababa, Ethiopia.

出版信息

Open Access Emerg Med. 2023 Feb 3;15:47-51. doi: 10.2147/OAEM.S400167. eCollection 2023.

Abstract

BACKGROUND AND AIMS

A sudden increase in blood pressure without serious, life-threatening symptoms or indications of immediate target organ damage is referred to as "hypertensive urgency." This case study revealed the rare direct cause of epistaxis and the direct cause of hypertensive urgency in an elderly man due to antihypertensive medication noncompliance.

CASE PRESENTATION

A black male farmer, age 63, was brought to the emergency room on June 1st, 2022, with chief complaints of breathing difficulties, epistaxis, and disorientation. The patient was hospitalized after exhibiting symptoms of breathlessness, malaise, nausea, and vomiting. Magnetic resonance imaging, an echocardiogram, and a computed tomography scan of the brain are all clear. For the treatment of epistaxis, he received 1g of tranexamic acid intravenously three times a day for two days. He received intravenous labetalol, which was effective in treating his hypertensive urgency and rebound hypertension, utilizing repeated dosages of 5-20 mg. The patient's intravenous labetalol and previous enalapril were switched to captopril 25 mg orally three times a day for one month after starting drugs per os.

DISCUSSION

The patient's hypertensive urgency is directly caused by forgetting to take his blood pressure medication and by not adhering to his previous antihypertensive drugs as prescribed. In this study, the patient's hypertension had been uncontrolled for the previous six months despite his treatment plan. Unaware that he had missed two doses of his antihypertensive medication, he was admitted to the emergency room with progressive anterior nose bleeding that persisted for four hours. The patient's elevated arterial blood pressure is what's causing the patient's nose to bleed.

摘要

背景与目的

血压突然升高,但无严重的、危及生命的症状或即时靶器官损害的迹象,被称为“高血压急症”。本病例研究揭示了一名老年男性因未遵医嘱服用降压药导致鼻出血及高血压急症的罕见直接原因。

病例介绍

一名63岁的黑人男性农民于2022年6月1日被送往急诊室,主要症状为呼吸困难、鼻出血和定向障碍。患者在出现呼吸急促、不适、恶心和呕吐症状后住院。磁共振成像、超声心动图和脑部计算机断层扫描均显示正常。为治疗鼻出血,他连续两天每天静脉注射1克氨甲环酸三次。他接受了静脉注射拉贝洛尔,通过重复给予5 - 20毫克的剂量,有效治疗了他的高血压急症和反跳性高血压。在开始口服药物治疗后,患者的静脉注射拉贝洛尔和之前的依那普利被换成卡托普利,每天口服三次,每次25毫克,持续一个月。

讨论

患者的高血压急症直接是由于忘记服用降压药以及未按之前的医嘱坚持服用降压药所致。在本研究中,尽管有治疗方案,但患者的高血压在过去六个月一直未得到控制。他未意识到自己漏服了两剂降压药,因进行性前鼻出血持续了四个小时而被送往急诊室。患者动脉血压升高是导致鼻出血的原因。

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2020 International Society of Hypertension Global Hypertension Practice Guidelines.2020年国际高血压学会全球高血压实践指南
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