• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

仅用局部阿昔洛韦治疗的疑似单纯疱疹病毒性溃疡性结节性巩膜炎。

Presumed herpes simplex virus ulcerative nodular episcleritis treated by topical acyclovir alone.

作者信息

Hoshing Abhishek, Seth Atul, Subramaniam Abhay

机构信息

Department of Ophthalmology, Apollo Hospitals, Navi Mumbai, Maharashtra, India.

Eyemax Superspeciality Eye Center, Navi Mumbai, Maharashtra, India.

出版信息

Oman J Ophthalmol. 2022 Nov 2;15(3):360-362. doi: 10.4103/ojo.ojo_138_21. eCollection 2022 Sep-Dec.

DOI:10.4103/ojo.ojo_138_21
PMID:36760928
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9905923/
Abstract

A 7-year-old female child was referred to the cornea clinic with a painless, ulcerated, and inflamed nodule near the limbus which did not respond to 1-week antibiotic therapy and worsened on starting topical steroids. Clinical examination showed ulcerative nodular episcleritis and raised a suspicion of herpes simplex virus etiology. The patient responded well and resolved completely on topical antiviral therapy alone.

摘要

一名7岁女童因角膜缘附近出现无痛性、溃疡且发炎的结节被转诊至角膜诊所。该结节在接受为期1周的抗生素治疗后无改善，且在开始局部使用类固醇药物后病情恶化。临床检查显示为溃疡性结节性巩膜炎，并怀疑病因是单纯疱疹病毒。仅通过局部抗病毒治疗，患者病情就得到了良好改善并完全康复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34e1/9905923/ca6d84dc83e5/OJO-15-360-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34e1/9905923/95a3e5c27c17/OJO-15-360-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34e1/9905923/fae9978e1326/OJO-15-360-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34e1/9905923/ca6d84dc83e5/OJO-15-360-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34e1/9905923/95a3e5c27c17/OJO-15-360-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34e1/9905923/fae9978e1326/OJO-15-360-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34e1/9905923/ca6d84dc83e5/OJO-15-360-g003.jpg

相似文献

1
Presumed herpes simplex virus ulcerative nodular episcleritis treated by topical acyclovir alone.仅用局部阿昔洛韦治疗的疑似单纯疱疹病毒性溃疡性结节性巩膜炎。
Oman J Ophthalmol. 2022 Nov 2;15(3):360-362. doi: 10.4103/ojo.ojo_138_21. eCollection 2022 Sep-Dec.
2
Topical interferon alpha-2a treatment of herpes simplex keratitis resistant to multiple antiviral medications in an immunosuppressed patient.在一名免疫抑制患者中，局部应用干扰素α-2a治疗对多种抗病毒药物耐药的单纯疱疹性角膜炎。
Cornea. 1995 May;14(3):326-30. doi: 10.1097/00003226-199505000-00017.
3
Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC).使用（S）-1-（3-羟基-2-膦酰甲氧基丙基）胞嘧啶（HPMPC）成功治疗由对阿昔洛韦和膦甲酸钠耐药的单纯疱疹病毒引起的进行性黏膜皮肤感染。
Clin Infect Dis. 1994 Apr;18(4):570-8. doi: 10.1093/clinids/18.4.570.
4
Antiviral therapy after penetrating keratoplasty for herpes simplex keratitis.单纯疱疹性角膜炎穿透性角膜移植术后的抗病毒治疗。
Arch Ophthalmol. 1994 May;112(5):601-7. doi: 10.1001/archopht.1994.01090170045020.
5
The treatment of herpes simplex virus epithelial keratitis.单纯疱疹病毒性上皮性角膜炎的治疗
Trans Am Ophthalmol Soc. 2000;98:505-32.
6
Herpesviridae-associated persistent mucocutaneous ulcers in acquired immunodeficiency syndrome. A clinicopathologic study.获得性免疫缺陷综合征中与疱疹病毒科相关的持续性黏膜皮肤溃疡。一项临床病理研究。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996 Apr;81(4):433-41. doi: 10.1016/s1079-2104(96)80019-9.
7
Herpes simplex keratitis misdiagnosed as rheumatoid arthritis-related peripheral ulcerative keratitis.被误诊为类风湿关节炎相关周边溃疡性角膜炎的单纯疱疹性角膜炎
Cornea. 2005 Nov;24(8):1015-7. doi: 10.1097/01.ico.0000159758.36230.c1.
8
The role of topical 5% acyclovir and 1% hydrocortisone cream (Xerese™) in the treatment of recurrent herpes simplex labialis.局部应用 5%阿昔洛韦和 1%氢化可的松乳膏（Xerese™）治疗复发性唇疱疹的作用。
Postgrad Med. 2010 Sep;122(5):1-6. doi: 10.3810/pgm.2010.09.2216.
9
Treatment of Steroid-Resistant Nodular Episcleritis With Tacrolimus: A Case Report.他克莫司治疗类固醇抵抗性结节性巩膜炎：一例报告
Cureus. 2023 Oct 15;15(10):e47057. doi: 10.7759/cureus.47057. eCollection 2023 Oct.
10
Topical treatment of infection with acyclovir-resistant mucocutaneous herpes simplex virus with the ribonucleotide reductase inhibitor 348U87 in combination with acyclovir.使用核糖核苷酸还原酶抑制剂348U87联合阿昔洛韦对耐阿昔洛韦的黏膜皮肤单纯疱疹病毒感染进行局部治疗。
Antimicrob Agents Chemother. 1993 May;37(5):975-9. doi: 10.1128/AAC.37.5.975.

本文引用的文献

1
Recurrent presumed herpes simplex keratitis and episcleritis in keratosis follicularis (Darier's disease).毛囊角化病（达里埃病）中的复发性疑似单纯疱疹性角膜炎和巩膜炎。
BMJ Case Rep. 2015 Jul 16;2015:bcr2015210772. doi: 10.1136/bcr-2015-210772.
2
Herpes simplex ocular inflammatory disease.单纯疱疹性眼部炎性疾病
Int Ophthalmol Clin. 2006 Spring;46(2):27-37. doi: 10.1097/00004397-200604620-00005.
3
Double-masked trial of topical acyclovir and steroids in the treatment of herpes zoster ocular inflammation.局部用阿昔洛韦和类固醇治疗带状疱疹性眼部炎症的双盲试验。
Br J Ophthalmol. 1991 Sep;75(9):542-6. doi: 10.1136/bjo.75.9.542.
4
Clinical profile of herpes zoster ophthalmicus.
J Indian Med Assoc. 1991 May;89(5):117-9.