Department of Environmental and Occupational Health and Safety, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Department of Public Health, School of Health Sciences, Goba Referral Hospital, Madda Walabu University, Bale Goba, Ethiopia.
Front Public Health. 2023 Jan 24;10:1001423. doi: 10.3389/fpubh.2022.1001423. eCollection 2022.
The COVID-19 pandemic has severely affected the entire world, especially sub-Saharan Africa. As a result, researchers and government agencies are working to create effective COVID-19 vaccinations. While vaccination campaigns are moving rapidly in high-income nations, COVID-19 is still ruthlessly affecting people in low-income nations. However, this difference in the spread of the disease is not because of a lack of a COVID-19 vaccine but mainly due to people's reluctance. As a result, this review summarized the data on COVID-19 vaccination adoption and factors related among nations in sub-Saharan Africa.
Comprehensive searches were conducted using PubMed, Embase, Medline, Web of Science, Google Scholar, and the Cochrane Library databases. The risk of bias and methodological quality of each published article that fit the selection criteria were evaluated using Critical Appraisal Checklist tools. All statistical analysis was done by STATA 16.
This review was based on 29 studies with 26,255 participants from sub-Saharan Africa. Using a random-effects model, the pooled prevalence of COVID-19 vaccine acceptance among study participants was 55.04% (95 % CI: 47.80-62.27 %), I = 99.55%. Being male [POR = 1.88 (95% CI: 1.45, 2.44)], having a positive attitude toward the COVID-19 vaccine [POR = 5.56 (95% CI: 3.63, 8.51)], having good knowledge in the COVID-19 vaccine [POR = 4.61 (95% CI: 1.24, 8.75)], having government trust [POR = 7.10 (95% CI: 2.37, 21.32)], and having undergone COVID-19 testing in the past [POR = 4.41 (95%CI: (2.51, 7.75)] were significant predictor variables.
This analysis showed that respondents had a decreased pooled prevalence of COVID-19 vaccination acceptance. Sex, attitude, knowledge, government trust, and COVID-19 testing were statistically significantly correlated characteristics that affected the acceptability of the COVID-19 vaccine. All stakeholders should be actively involved in increasing the uptake of the COVID-19 vaccine and thereby reducing the consequences of COVID-19. The acceptance of the COVID-19 vaccination can be increased by using this conclusion as an indicator for governments, healthcare professionals, and health policymakers in their work on attitude, knowledge, government trust, and COVID-19 testing.
COVID-19 大流行严重影响了整个世界，尤其是撒哈拉以南非洲地区。因此，研究人员和政府机构正在努力开发有效的 COVID-19 疫苗。虽然在高收入国家的疫苗接种运动正在迅速推进，但 COVID-19 仍在无情地影响着低收入国家的人们。然而，疾病传播的这种差异并不是因为缺乏 COVID-19 疫苗，而是主要因为人们不愿意接种。因此，本综述总结了撒哈拉以南非洲国家 COVID-19 疫苗接种率和相关因素的数据。
使用 PubMed、Embase、Medline、Web of Science、Google Scholar 和 Cochrane 图书馆数据库进行全面检索。使用Critical Appraisal Checklist 工具评估符合选择标准的每篇已发表文章的偏倚风险和方法学质量。所有统计分析均使用 STATA 16 进行。
本综述基于来自撒哈拉以南非洲地区的 29 项研究，共 26255 名参与者。使用随机效应模型，研究参与者中 COVID-19 疫苗接种接受率的汇总患病率为 55.04%（95%CI：47.80-62.27%），I=99.55%。男性[POR=1.88（95%CI：1.45-2.44）]、对 COVID-19 疫苗持积极态度[POR=5.56（95%CI：3.63-8.51）]、对 COVID-19 疫苗有较好的认识[POR=4.61（95%CI：1.24-8.75）]、对政府有信任[POR=7.10（95%CI：2.37-21.32）]和过去接受过 COVID-19 检测[POR=4.41（95%CI：2.51-7.75）]是显著的预测变量。
本分析表明，受访者对 COVID-19 疫苗接种的接受率降低。性别、态度、知识、政府信任和 COVID-19 检测是具有统计学意义的相关特征，影响 COVID-19 疫苗的可接受性。所有利益攸关方都应积极参与提高 COVID-19 疫苗的接种率，从而减少 COVID-19 的后果。政府、医疗保健专业人员和卫生政策制定者可以利用这一结论，在工作中关注态度、知识、政府信任和 COVID-19 检测，以提高 COVID-19 疫苗的接种率。
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