重新审视手术切除在脑转移瘤治疗中的作用。
Revisiting the Role of Surgical Resection for Brain Metastasis.
作者信息
Byun Joonho, Kim Jong Hyun
机构信息
Department of Neurosurgery, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
出版信息
Brain Tumor Res Treat. 2023 Jan;11(1):1-7. doi: 10.14791/btrt.2022.0028.
Abstract
Brain metastasis (BM) is the most common type of brain tumor in adults. The contemporary management of BM remains challenging. Advancements in systemic cancer treatment have increased the survival of patients with cancer. Although the treatment of BM is still complicated, advances in radiotherapy, including stereotactic radiosurgery and chemotherapy, have improved treatment outcomes. Surgical resection is the traditional treatment for BM and its role in the surgical resection of BM has been well established. However, refinement of the surgical resection technique and strategy for BM is needed. Herein, we discuss the evolving role of surgery in patients with BM and the future of BM treatment.
摘要
脑转移瘤（BM）是成人中最常见的脑肿瘤类型。BM的现代治疗仍然具有挑战性。全身癌症治疗的进展提高了癌症患者的生存率。尽管BM的治疗仍然复杂，但包括立体定向放射外科和化疗在内的放射治疗进展已改善了治疗效果。手术切除是BM的传统治疗方法，其在BM手术切除中的作用已得到充分确立。然而，需要改进BM的手术切除技术和策略。在此，我们讨论手术在BM患者中的不断演变的作用以及BM治疗的未来。
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2
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Cancers (Basel). 2022 Jan 26;14(3):617. doi: 10.3390/cancers14030617.
3
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Acta Neurochir (Wien). 2022 Oct;164(10):2773-2780. doi: 10.1007/s00701-021-05104-7. Epub 2022 Jan 26.
4
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