简单的醚导向的手性 Ir 催化的环丙烷 C(sp3)-H 硼化反应。
Simple Ether-Directed Enantioselective C(sp )-H Borylation of Cyclopropanes Enabled by Iridium Catalysis.
机构信息
College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, 310014, China.
State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, China.
出版信息
Angew Chem Int Ed Engl. 2023 Mar 27;62(14):e202300199. doi: 10.1002/anie.202300199. Epub 2023 Feb 24.
Reported here is an efficient and simple ether-directed iridium-catalyzed enantioselective C(sp )-H borylation of cyclopropanes. Various functional groups were well-tolerated, affording a vast array of chiral cyclopropanes with high enantioselectivities. We also demonstrated that the turnover numbers of the current reaction could be up to 335.
本文报道了一种高效、简便的醚导向的铱催化的环丙烷 C(sp )-H 硼化反应的对映选择性。各种官能团都具有良好的耐受性，能够以高对映选择性得到大量的手性环丙烷产物。我们还证明，目前反应的周转数最高可达 335。
Zotero 插件