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国际儿科耳鼻喉科小组:非结核分枝杆菌颈面部淋巴结炎诊断与管理的共识指南

International Pediatric Otolaryngology Group: Consensus guidelines on the diagnosis and management of non-tuberculous mycobacterial cervicofacial lymphadenitis.

作者信息

Roy Catherine F, Balakrishnan Karthik, Boudewyns An, Cheng Alan, Chun Robert H, Daniel Sam J, Fayoux Pierre, Hart Catherine, Hemansson Ann, Hewitt Richard, Hsu Wei-Chung, Kuo Michael, Liu Christopher, Maddalozzo John, Messner Anna H, Pransky Seth, Rahbar Reza, Rickert Scott, Roy Soham, Russell John, Rutter Michael J, Sie Kathleen C Y, Sidell Douglas, Smith Richard, Soma Marlene, Spratley Jorge, Watters Karen, White David R, Wolter Nikolaus, Zalzal George, Yeung Jeffrey C

机构信息

Department of Otolaryngology Head & Neck Surgery, McGill University Health Center, Montreal, QC, Canada.

Department of Otolaryngology-Head & Neck Surgery, Lucile Packard Children's Hospital, Stanford University, Palo Alto, CA, USA.

出版信息

Int J Pediatr Otorhinolaryngol. 2023 Mar;166:111469. doi: 10.1016/j.ijporl.2023.111469. Epub 2023 Feb 2.

Abstract

INTRODUCTION

Non-tuberculous mycobacterial (NTM) infection commonly manifests as subacute or chronic cervicofacial lymphadenitis in immunocompetent children. The optimal management of this pathology remains controversial.

OBJECTIVES

This international consensus guideline aims to understand the practice patterns for NTM cervicofacial lymphadenitis and to address the primary diagnostic and management challenges.

METHODS

A modified three-iterative Delphi method was used to establish expert recommendations on the diagnostic considerations, expectant or medical management, and operative considerations. The recommendations herein are derived from current expert consensus and critical review of the literature.

SETTING

Multinational, multi-institutional, tertiary pediatric hospitals.

RESULTS

Consensus recommendations include diagnostic work-up, goals of treatment and management options including surgery, prolonged antibiotic therapy and observation.

CONCLUSION

The recommendations formulated in this International Pediatric Otolaryngology Group (IPOG) consensus statement on the diagnosis and management of patients with NTM lymphadenitis are aimed at improving patient care and promoting future hypothesis generation.

摘要

引言

非结核分枝杆菌(NTM)感染在免疫功能正常的儿童中通常表现为亚急性或慢性颈面部淋巴结炎。这种病症的最佳治疗方案仍存在争议。

目的

本国际共识指南旨在了解NTM颈面部淋巴结炎的治疗模式,并应对主要的诊断和治疗挑战。

方法

采用改良的三轮德尔菲法,就诊断考量、观察或药物治疗以及手术考量制定专家建议。本文中的建议源自当前的专家共识和对文献的批判性综述。

背景

跨国、多机构的三级儿科医院。

结果

共识建议包括诊断检查、治疗目标和管理选项,包括手术、长期抗生素治疗和观察。

结论

本国际儿科耳鼻咽喉科小组(IPOG)关于NTM淋巴结炎患者诊断和管理的共识声明中制定的建议旨在改善患者护理并促进未来的假设生成。

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