Leboffe Emily N, Pietragallo Helana C, Liu Guodong, Ba Djibril, Leslie Douglas, Chuang Cynthia H
Penn State College of Medicine, 700 HMC Crescent Rd, Hershey, PA 17033, United States of America.
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, 300 Halket Street, Pittsburgh, PA 15213, United States of America.
J Affect Disord. 2023 May 1;328:103-107. doi: 10.1016/j.jad.2023.02.020. Epub 2023 Feb 9.
Postpartum depression (PPD), is underdiagnosed and undertreated. In 2015, the American College of Obstetricians and Gynecologists (ACOG) recommended that women be screened for PPD at least once during the perinatal period. The effect of the recommendation on PPD diagnosis is unknown.
Using the MerativeTM MarketScan® database, PPD prevalence was identified in privately insured women ages 13-45 with a live birth between 2013 and 2016. Postpartum depression was defined as an ICD diagnosis code for PPD or other depression, or a new pharmacy claim for an antidepressant medication during the first 12 months following delivery. Multivariable logistic regression was used to estimate the likelihood of PPD both before and after the ACOG PPD Committee Opinion.
The study included 244,624 women ages 13-45 who had a live birth in 2013 through 2016. PPD prevalence before and after the 2015 ACOG Committee Opinion was 15.1 % and 17.2 %, respectively. The likelihood of PPD was not statistically different following the 2015 Committee Opinion (adjusted OR, 1.00, 95 % CI, 0.97-1.03) when controlling for age, year, delivery complications, and geographic region.
Sociodemographic variables are not included in the MarketScan database and therefore could not be analyzed as covariates. Re-defining a PPD diagnosis as above interfered with the ability to measure a prior history of mood disorders as a covariate.
Implementation of the ACOG recommendations was not associated with a significant increase in PPD diagnosis. This suggests that physician organization recommendations alone are not sufficient to increase detection of PPD.
产后抑郁症(PPD)的诊断和治疗不足。2015年,美国妇产科医师学会(ACOG)建议在围产期至少对女性进行一次PPD筛查。该建议对PPD诊断的影响尚不清楚。
使用默克多源数据库(MerativeTM MarketScan®),确定2013年至2016年期间有活产记录的13至45岁的参加商业保险的女性中的PPD患病率。产后抑郁症被定义为PPD或其他抑郁症的ICD诊断代码,或分娩后前12个月内新的抗抑郁药物药房索赔。使用多变量逻辑回归来估计ACOG PPD委员会意见发布前后PPD的可能性。
该研究纳入了2013年至2016年期间有活产记录的244,624名13至45岁的女性。2015年ACOG委员会意见发布前后的PPD患病率分别为15.1%和17.2%。在控制年龄、年份、分娩并发症和地理区域后,2015年委员会意见发布后PPD的可能性在统计学上没有差异(调整后的OR,1.00,95%CI,0.97-1.03)。
默克多源数据库中未包括社会人口统计学变量,因此无法作为协变量进行分析。将PPD诊断重新定义为上述情况会干扰将情绪障碍既往史作为协变量进行测量的能力。
实施ACOG建议与PPD诊断的显著增加无关。这表明仅靠医师组织的建议不足以增加PPD的检测率。