Nagata Masumi, Jimbo Keisuke, Arai Nobuyasu, Kashiwagi Kosuke, Tokushima Kaori, Suzuki Mitsuyoshi, Kudo Takahiro, Shimizu Toshiaki
Department of Pediatrics, Faculty of Medicine, Juntendo University, Tokyo 113-8421, Japan.
Diagnostics (Basel). 2023 Jan 29;13(3):494. doi: 10.3390/diagnostics13030494.
Juvenile polyps, typically localized in the rectum and sigmoid colon, are a common cause of pediatric bloody stool. An isolated small intestinal juvenile polyp is uncommon and generally difficult to diagnose. The first case of an isolated juvenile polyp diagnosed by abdominal ultrasonography before acute abdomen had developed and resected by double-balloon endoscopy is presented along with a review of previous reports including this case. A two-year-old Japanese boy was referred to our institute for further evaluation of anemia persisting from one year of age. Laboratory findings showed mild iron deficiency anemia and elevated fecal human hemoglobin (Hb) and fecal calprotectin values. Upper and lower endoscopic findings showed no abnormalities. Because the abdominal ultrasonography performed one year later demonstrated a 15 mm jejunal polyp, combined with a similar finding on small intestinal capsule endoscopy, this was diagnosed as an isolated lesion. The lesion was resected by cautery with double-balloon endoscopy and diagnosed as a juvenile polyp pathologically. All clinical symptoms disappeared, and all laboratory data improved after treatment, without recurrence for more than one year after the procedure. Abdominal ultrasonographic screening and the fecal calprotectin value led to the diagnosis and non-surgical invasive treatment of an isolated small intestinal juvenile polyp.
幼年性息肉通常位于直肠和乙状结肠,是小儿便血的常见原因。孤立性小肠幼年性息肉并不常见,一般难以诊断。本文报告了首例在急性腹痛发生前经腹部超声诊断并经双气囊内镜切除的孤立性幼年性息肉病例,并回顾了包括该病例在内的既往报道。一名两岁日本男孩因一岁起持续存在的贫血被转诊至我院作进一步评估。实验室检查结果显示轻度缺铁性贫血,粪便人血红蛋白(Hb)和粪便钙卫蛋白值升高。上下消化道内镜检查未发现异常。因为一年后进行的腹部超声显示一个15毫米的空肠息肉,小肠胶囊内镜检查也有类似发现,所以诊断为孤立性病变。通过双气囊内镜电灼切除病变,病理诊断为幼年性息肉。治疗后所有临床症状消失,所有实验室数据均改善,术后一年多未复发。腹部超声筛查和粪便钙卫蛋白值有助于孤立性小肠幼年性息肉的诊断和非手术侵入性治疗。