Lu Dong-Xing, Zhang Kun, Ma Teng, Li Ming, Li Zhong, Xu Yi-Bo, Wang Chao-Feng, Ren Cheng, Zhang Bin-Fei
Department of Orthopaedic Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054, China.
Department of Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054, China.
Diagnostics (Basel). 2023 Feb 2;13(3):545. doi: 10.3390/diagnostics13030545.
This study aimed to evaluate the association between serum phosphorus level and preoperative deep vein thrombosis (DVT) in geriatric hip fractures.
Older adults with hip fractures were screened between January 2015 and September 2019. Demographic and clinical characteristics of the patients were collected. Multivariate binary logistic regression and generalized additive models were used to identify the linear and nonlinear associations between serum phosphorus levels and preoperative DVT. Analyses were performed using Empower Stats and R software.
In this study, 1818 patients were included, with an average age of 79.39 ± 6.87. Of these, 30.25% were males, and 580 patients had DVT. The study found that when serum phosphorus was used as a continuous variable, there was a statistically significant difference in the relationship between blood phosphorus and the occurrence of DVT ( < 0.05). Furthermore, we also found curvilinear relationships. Serum phosphorus = 0.71 mmol/L was the inflection point in the curve. When serum phosphorus was <0.71 mmol/L, the serum phosphorus was associated with DVT (OR = 1.64; 95% CI: 1.04-2.59; = 0.0333). With a 0.1 mmol/L increase, the DVT increased 0.64 times. When phosphorus was >0.71 mmol/L, there was no significant difference in the correlation between serum phosphorus levels and DVT (OR = 1.03; 95% CI: 0.98-1.09; = 0.186).
Serum phosphorus was nonlinearly associated with preoperative DVT in geriatric patients with hip fractures, and serum phosphorus level could be considered a predictor of DVT risk.
本研究旨在评估老年髋部骨折患者血清磷水平与术前深静脉血栓形成（DVT）之间的关联。
对2015年1月至2019年9月期间的老年髋部骨折患者进行筛查。收集患者的人口统计学和临床特征。采用多变量二元逻辑回归和广义相加模型来确定血清磷水平与术前DVT之间的线性和非线性关联。使用Empower Stats和R软件进行分析。
本研究共纳入1818例患者，平均年龄为79.39±6.87岁。其中，男性占30.25%，580例患者发生DVT。研究发现，当将血清磷作为连续变量时，血磷与DVT发生之间的关系存在统计学显著差异（<0.05）。此外，我们还发现了曲线关系。血清磷=0.71 mmol/L是曲线中的拐点。当血清磷<0.71 mmol/L时，血清磷与DVT相关（OR = 1.64；95%CI：1.04 - 2.59； = 0.0333）。每增加0.1 mmol/L，DVT增加0.64倍。当磷>0.71 mmol/L时，血清磷水平与DVT之间的相关性无显著差异（OR = 1.03；95%CI：0.98 - 1.09； = 0.186）。
老年髋部骨折患者血清磷与术前DVT呈非线性关联，血清磷水平可被视为DVT风险的预测指标。
