Nóbrega Lígia Reis, Rocon Eduardo, Pereira Adriano Alves, Andrade Adriano de Oliveira
Faculty of Electrical Engineering, Federal University of Uberlândia, Uberlândia 38400-902, MG, Brazil.
Centre for Automation and Robotics (CAR), Spanish National Research Council and Higher Technical School of Industrial Engineering (CSIC-UPM), 28500 Madrid, Spain.
Healthcare (Basel). 2023 Jan 31;11(3):409. doi: 10.3390/healthcare11030409.
Freezing of gait (FOG), one of the most disabling features of Parkinson's disease (PD), is a brief episodic absence or marked reduction in stride progression despite the intention to walk. Progressively more people who experience FOG restrict their walking and reduce their level of physical activity. The purpose of this study is to develop and validate a physical mobility task that induces freezing of gait in a controlled environment, employing known triggers of FOG episodes according to the literature. To validate the physical mobility tasks, we recruited 10 volunteers that suffered PD-associated freezing (60.6 ± 7.29 years-old) with new FOG-Q ranging from 12 to 26. The validation of the proposed method was carried out using inertial sensors and video recordings. All subjects were assessed during the OFF and ON medication states. The total number of FOG occurrences during data collection was 144. The proposed tasks were able to trigger 120 FOG episodes, while the TUG test caused 24. The Inertial Measurement Unit (IMU) with accelerometer and gyroscope could not only detect FOG episodes but also allowed us to visualize the three types of FOG: akinesia, festination and trembling in place.
冻结步态（FOG）是帕金森病（PD）最致残的特征之一，是指尽管有行走意图，但步幅进展短暂发作性缺失或显著减少。越来越多经历冻结步态的人限制行走并降低身体活动水平。本研究的目的是开发并验证一种身体移动任务，该任务在可控环境中诱发冻结步态，根据文献采用已知的冻结步态发作触发因素。为了验证身体移动任务，我们招募了10名患有帕金森病相关冻结步态的志愿者（年龄60.6±7.29岁），新的冻结步态问卷（FOG-Q）评分在12至26之间。使用惯性传感器和视频记录对所提出的方法进行验证。所有受试者在药物未起效和起效状态下均接受评估。数据收集期间冻结步态发生的总数为144次。所提出的任务能够触发120次冻结步态发作，而定时起立步行测试（TUG测试）引发了24次。带有加速度计和陀螺仪的惯性测量单元（IMU）不仅能够检测冻结步态发作，还能让我们观察到三种类型的冻结步态：运动不能、慌张步态和原地颤抖。
