Petrosini L, Gremoli T
Institute of Human Physiology, Catholic University, Rome, Italy.
Brain Res. 1987 Aug 25;418(2):398-402. doi: 10.1016/0006-8993(87)90111-9.
The strong imbalance of the output of vestibular nuclei, resulting from a hemilabyrinthectomy, causes among other postural and ocular symptoms, a failure to hold a steady ocular position in the dark. In this study the time course of the spontaneous eye motility following a right hemilabyrinthectomy was analyzed. In all animals, at the first recordings, drifts of 0.8-1.0 degrees/s were present. These drifts were directed to the lesion side, then they shifted their trajectory more than once. At the final recordings, most animals exhibited very slow drifts (0.05-0.1 degrees/s) directed to the intact side suggesting an overcompensation of the initial extreme rightward deviation.
半规管切除术导致前庭核输出严重失衡，除其他姿势和眼部症状外，还会导致在黑暗中无法保持稳定的眼位。在本研究中，分析了右侧半规管切除术后自发性眼球运动的时间进程。在所有动物中，首次记录时均出现0.8 - 1.0度/秒的漂移。这些漂移指向病变侧，然后其轨迹不止一次地发生改变。在最后记录时，大多数动物表现出非常缓慢的漂移（0.05 - 0.1度/秒），指向完整侧，这表明最初极端向右偏差出现了过度代偿。
