Castrén E, Kurihara M, Gutkind J S, Saavedra J M
Unit on Preclinical Neuropharmacology, National Institute of Mental Health, Bethesda, MD 20982.
Brain Res. 1987 Oct 6;422(2):347-51. doi: 10.1016/0006-8993(87)90942-5.
Angiotensin II binding sites were localized and quantified in rat stellate and superior cervical ganglia by quantitative autoradiography using 125I-Sar1-angiotensin II as a ligand. Both ganglia possess a single class of angiotensin II binding sites. High concentrations of binding sites were localized in the areas rich in principal ganglion cells. These binding sites might mediate the facilitatory action of angiotensin II on the ganglionic transmission.
通过使用125I- Sar1-血管紧张素II作为配体的定量放射自显影术，在大鼠星状神经节和颈上神经节中对血管紧张素II结合位点进行了定位和定量。两个神经节均具有一类血管紧张素II结合位点。高浓度的结合位点定位于富含神经节主细胞的区域。这些结合位点可能介导血管紧张素II对神经节传递的促进作用。
