Addiction Treatment Center, Local Health Service N. 2, Veneto, Via dei Carpani, 16/Z, 31033 Treviso, Italy.
Int J Environ Res Public Health. 2023 Jan 31;20(3):2602. doi: 10.3390/ijerph20032602.
Attention-deficit/hyperactivity disorder (ADHD) is a childhood neurodevelopmental disorder that can persist into adulthood. The co-occurrence of ADHD and substance use disorders is very frequent and has received considerable attention in recent clinical/scientific investigations. However, few studies have investigated the prevalence of ADHD in heroin addicts. This study aimed to investigate the prevalence of attention-deficit/hyperactivity disorder (ADHD) in a sample of heroin addicts treated with opioid agonists and to report this clinical experience in a public service for addiction. Outpatients over 18 years old and being treated with opioid agonists for heroin addiction were enrolled. Each patient took part in a psychiatric examination and completed an ASRS (Adult ADHD Self-Report Scale) self-assessment. Subjects with positive results were called in for another psychiatric visit, and the Brown ADD scale was used as a second-level test for ADHD; furthermore, the Mini International Neuropsychiatric Interview (MINI) and Hypomania/Mania Checklist (HCL-32) were used for differential diagnoses and to assess comorbidities. In total, 111 patients were enrolled. All were followed up by the psychiatrist, who is also the author of this report and the person who formulated the diagnoses. The prevalence of ADHD in this sample was 18%. Among the 20 patients diagnosed with ADHD, 5 (25%) were female and 15 (75%) were male. The most frequent psychiatric comorbidity was major depression, found in 11 patients (55%), of which 4 presented with hypomania (bipolar disorder). In this sample, making diagnoses was very difficult. Frequently, multiple comorbidities further complicated these cases. In conclusion, the results of this study are consistent with the literature: There seems to be a significant prevalence of ADHD even among heroin addicts, and often, the diagnosis is difficult to make. We also do not know the exact effect of opioid agonist therapy on ADHD symptoms. Hypotheses have been put forward, but studies are needed.
注意缺陷多动障碍(ADHD)是一种儿童神经发育障碍,可延续至成年期。ADHD 与物质使用障碍的共病发生率非常高,在最近的临床/科学研究中受到了相当多的关注。然而,很少有研究调查海洛因成瘾者中 ADHD 的患病率。本研究旨在调查阿片类激动剂治疗的海洛因成瘾者样本中注意缺陷多动障碍(ADHD)的患病率,并在成瘾服务机构中报告这一临床经验。纳入年龄在 18 岁以上、正在接受阿片类激动剂治疗海洛因成瘾的门诊患者。每位患者均接受了精神科检查,并完成了 ASRS(成人 ADHD 自评量表)自评。结果阳性的患者被召回进行另一次精神科就诊,使用 Brown ADD 量表作为 ADHD 的二级测试;此外,使用 Mini 国际神经精神访谈(MINI)和轻躁狂/躁狂清单(HCL-32)进行鉴别诊断和评估共病。共有 111 例患者入组。所有患者均由精神科医生随访,该医生也是本报告的作者和诊断制定者。该样本中 ADHD 的患病率为 18%。在被诊断为 ADHD 的 20 例患者中,5 例(25%)为女性,15 例(75%)为男性。最常见的精神共病是重度抑郁症,在 11 例患者中发现(55%),其中 4 例出现轻躁狂(双相障碍)。在该样本中,做出诊断非常困难。经常,多种共病使这些病例更加复杂。总之,本研究结果与文献一致:即使在海洛因成瘾者中,ADHD 的患病率似乎也很高,且通常,诊断也很难做出。我们也不知道阿片类激动剂治疗对 ADHD 症状的确切影响。已经提出了一些假说,但需要进行研究。