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脑凝集素介导的来自胚胎和出生后小鼠脑的解离细胞的凝集性

Brain lectin-mediated agglutinability of dissociated cells from embryonic and postnatal mouse brain.

作者信息

Joubert R, Caron M, Bladier D

机构信息

U.F.R. Santé, Médecine et Biologie Humaine, Laboratoire de Biochimie, Bobigny, France.

出版信息

Brain Res. 1987 Nov;433(1):146-50. doi: 10.1016/0165-3806(87)90073-3.

DOI:10.1016/0165-3806(87)90073-3
PMID:3676851
Abstract

Brain extracts contain a soluble lectin which enables the agglutination of dissociated mouse brain cells via saccharidic receptors. The ability of the brain cells to be agglutinated depends on their stage of development in vivo. Furthermore, after birth, the mechanism of the lectin-promoted agglutination is complicated by the appearance of a self-aggregation of the dissociated cells. Lactose and galactosides are inhibitors of lectin-mediated agglutination as well as of the dissociated cells' self-aggregation.

摘要

脑提取物含有一种可溶性凝集素,它能够通过糖受体使解离的小鼠脑细胞发生凝集。脑细胞被凝集的能力取决于它们在体内的发育阶段。此外,出生后,凝集素促进凝集的机制因解离细胞出现自我聚集而变得复杂。乳糖和半乳糖苷是凝集素介导凝集以及解离细胞自我聚集的抑制剂。

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