人工泪液成分和配方的物理化学性质及生物学效应的批判性评价。
A Critical Appraisal of the Physicochemical Properties and Biological Effects of Artificial Tear Ingredients and Formulations.
机构信息
Chapman University School of Pharmacy, Chapman University, Irvine, CA 92618, USA.
Department of Pathology, University of Colorado Anschutz Medical Campus, Denver, CO 80045, USA.
出版信息
Int J Mol Sci. 2023 Feb 1;24(3):2758. doi: 10.3390/ijms24032758.
Abstract
Dry eye disease is among the most prevalent diseases affecting the ocular surface. Artificial tears remain the cornerstone therapy for its management. There are currently a wide variety of marketed artificial tears available to choose from. These artificial tears differ significantly in their composition and formulation. This article reviews the physicochemical and biological properties of artificial tear components and how these characteristics determine their use and efficacy in the management of dry eye. Furthermore, this article also discusses the various formulations of artificial tears such as macro and nanoemulsion and the type of preservatives present in them.
摘要
干眼症是最常见的影响眼表面的疾病之一。人工泪液仍然是其治疗的基石。目前有各种各样的市售人工泪液可供选择。这些人工泪液在成分和配方上有很大的不同。本文综述了人工泪液成分的物理化学和生物学特性，以及这些特性如何决定它们在干眼症管理中的用途和疗效。此外，本文还讨论了人工泪液的各种配方，如宏观和纳米乳液，以及其中存在的防腐剂类型。
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