Gao Lang, Zhang Li, Zhang Zisang, Lin Yixia, Ji Mengmeng, He Qing, Xie Mingxing, Li Yuman
Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Hubei Province Clinical Research Center for Medical Imaging, Wuhan 430022, China.
J Clin Med. 2023 Jan 17;12(3):743. doi: 10.3390/jcm12030743.
Myocardial fibrosis (MF) is a non-reversible process that occurs following acute or chronic myocardial damage. MF worsens myocardial deformation, remodels the heart and raises myocardial stiffness, and is a crucial pathological manifestation in patients with end-stage cardiovascular diseases and closely related to cardiac adverse events. Therefore, early quantitative analysis of MF plays an important role in risk stratification, clinical decision, and improvement in prognosis. With the advent and development of strain imaging modalities in recent years, MF may be detected early in cardiovascular diseases. This review summarizes the clinical usefulness of strain imaging techniques in the non-invasive assessment of MF.
心肌纤维化(MF)是急性或慢性心肌损伤后发生的不可逆过程。MF会使心肌变形恶化,重塑心脏并增加心肌僵硬度,是终末期心血管疾病患者的关键病理表现,且与心脏不良事件密切相关。因此,对MF进行早期定量分析在风险分层、临床决策及改善预后方面发挥着重要作用。近年来,随着应变成像技术的出现和发展,心血管疾病中MF可能得以早期检测。本文综述了应变成像技术在MF无创评估中的临床应用价值。