Hoshida Shiro
Department of Cardiovascular Medicine, Yao Municipal Hospital, 1-3-1 Ryuge-cho, Yao 581-0069, Osaka, Japan.
J Clin Med. 2023 Jan 19;12(3):802. doi: 10.3390/jcm12030802.
Heart failure (HF) with preserved ejection fraction (HFpEF) is thought to be driven by increased cardiac afterload, which consequentially leads to left ventricular (LV) diastolic dysfunction. The ratio of LV diastolic elastance (Ed) to arterial elastance (Ea) significantly increases in older hypertensive women without HF and is coincident with cardiac structural alterations. Ed/Ea is reported to be a prognostic factor for all-cause mortality in patients admitted with HFpEF. In this short article, I provide a possible view of this novel index as having diagnostic potential for HFpEF in clinics and playing a prognostic role in HF with reduced ejection fraction (HFrEF).
射血分数保留的心力衰竭（HFpEF）被认为是由心脏后负荷增加所驱动，这进而导致左心室（LV）舒张功能障碍。在无HF的老年高血压女性中，左心室舒张弹性（Ed）与动脉弹性（Ea）的比值显著增加，且与心脏结构改变相一致。据报道，Ed/Ea是HFpEF患者全因死亡率的一个预后因素。在这篇短文里，我提出了一种可能的观点，即这个新指标在临床上对HFpEF具有诊断潜力，并且在射血分数降低的心力衰竭（HFrEF）中发挥预后作用。
