Mancino Fabio, Finsterwald Michael A, Jones Christopher W, Prosser Gareth H, Yates Piers J
Department of Orthopaedics, The Orthopaedic Research Foundation of Western Australia (ORFWA), Fiona Stanley Hospital, 6150 Perth, Australia.
Curtin Medical School, Faculty of Health Sciences, Curtin University, 6102 Perth, Australia.
J Clin Med. 2023 Jan 22;12(3):889. doi: 10.3390/jcm12030889.
The aim of this study is to update the 10-year follow-up survivorship and metal ions levels of a cohort of metal-on-metal (MoM) hip resurfacing (HR) and large-diameter-head (LDH) total hip arthroplasty (THA).
The study is a retrospective analysis of prospectively collected data that compared the outcomes of 24 MoM HR (21 patients) and 15 (11 patients) modular LHD MoM THA at >10 years follow-up. Baseline characteristics as well as intraoperative and postoperative information were collected, including complications, revisions, clinical and radiographic outcomes, and serum metal ions level (Cobalt, Chromium). Metal ion levels were compared using a two-tailed unpaired t-test and Wilcoxon signed-rank test (jamovi v2.3.3.0, Sydney, NSW, AU).
No significant differences were detected in gender, BMI, and ASA score between the two groups. Patients in the modular THA group were significantly older (57 years vs. 46 years; < 0.05). The HR overall survivorship was 91.7% (22 of 24 hips) with survivorship from implant failure and/or aseptic loosening and/or metal debris related 100% of problems. The modular THA overall survivorship was 86.7% (13 of 15 hips) with survivorship from implant aseptic loosening and metal ions complications of 93.4% (14 of 15 hips). No significant difference was noted when comparing clinical outcomes. Metal ions were significantly lower in the HR group (Co 25.8 nmol/L vs. 89 nmol/L; < 0.001-Cr 33.5 nmol/L vs. 55.2 nmol/L; = 0.026).
Both implants reported excellent and comparable clinical outcomes at >10 years follow-up. The Adept HR reported remarkable survivorship, in line with the registry data, proving once again its reliability in young active males. The modular LDH THA, despite being discontinued, presented higher reliability and a lower failure rate when compared with similar withdrawn MoM implants. Trunnionosis did not appear to be a significant problem in this particular modular design.
本研究的目的是更新一组金属对金属(MoM)髋关节表面置换术(HR)和大直径股骨头(LDH)全髋关节置换术(THA)患者的10年随访生存率及金属离子水平。
本研究是对前瞻性收集的数据进行回顾性分析,比较了24例MoM HR(21例患者)和15例(11例患者)模块化LDH MoM THA在超过10年随访期的结果。收集了基线特征以及术中、术后信息,包括并发症、翻修情况、临床和影像学结果以及血清金属离子水平(钴、铬)。使用双尾非配对t检验和Wilcoxon符号秩检验(jamovi v2.3.3.0,澳大利亚新南威尔士州悉尼)比较金属离子水平。
两组在性别、体重指数和美国麻醉医师协会(ASA)评分方面未检测到显著差异。模块化THA组患者年龄显著更大(57岁对46岁;<0.05)。HR的总体生存率为91.7%(24髋中的22髋),因植入物失败和/或无菌性松动和/或金属碎屑相关问题导致的生存率为100%。模块化THA的总体生存率为86.7%(15髋中的13髋),因植入物无菌性松动和金属离子并发症导致的生存率为93.4%(15髋中的14髋)。比较临床结果时未发现显著差异。HR组的金属离子水平显著更低(钴25.8 nmol/L对89 nmol/L;<0.001 - 铬33.5 nmol/L对55.2 nmol/L;=0.026)。
两种植入物在超过10年的随访中均报告了出色且可比的临床结果。Adept HR报告了显著的生存率,与登记数据一致,再次证明了其在年轻活跃男性中的可靠性。模块化LDH THA尽管已停产,但与类似的已停用MoM植入物相比,具有更高的可靠性和更低的故障率。在这种特定的模块化设计中,柄部腐蚀似乎不是一个重大问题。