Urmeneta Ulloa Javier, Martínez de Vega Vicente, Álvarez Vázquez Ana, Andreu-Vázquez Cristina, Thuissard-Vasallo Israel John, Recio Rodríguez Manuel, Pizarro Gonzalo, Cabrera José Ángel
Cardiology Department, Hospital Universitario Quirónsalud, 28223 Madrid, Spain.
Radiology Department, Hospital Universitario Quirónsalud, 28223 Madrid, Spain.
J Clin Med. 2023 Jan 31;12(3):1113. doi: 10.3390/jcm12031113.
This study sought to examine the correlation between left ventricular (LV) myocardial feature tracking (FT) and deep learning-based strain (DLS) analysis in the diagnostic (CMRd) and follow-up (CMRf) cardiac magnetic resonance imaging of patients with acute myocarditis. The retrospective study included 17 patients with acute myocarditis and 20 healthy controls. The CMRd took place within 14 days of symptom onset, while the CMRf took place at least 2 months after the event. The global-circumferential FT (FTc) and global-circumferential DLS (DLSc) were analyzed. The continuous variables were compared using paired -tests or the Wilcoxon test, whereas Pearson's test or Spearman's test was used to evaluate the correlation between the continuous variables. The time between the CMRd and CMRf was 5 months [3-11]. The LV ejection fraction (LVEF) was 55 ± 6 and 59 ± 4%, p = 0.008, respectively, and 94.1% of the patients showed late gadolinium enhancement (LGE) and myocardial edema on the CMRd. Significantly lower FTc (-16.1 ± 2.2% vs. -18.9 ± 1.9%, = 0.001) and DLSc (-38.1 ± 5.2% vs. -41.3 ± 4.5%, = 0.015) were observed with respect to the controls. Significant increases in the FTc (-16.1 ± 2.2 vs. -17.5 ± 1.9%, = 0.016) and DLSc (-38.1 ± 5.2 vs. -39.8 ± 3.9%, = 0.049) were found between the CMRd and CMRf, which were unrelated to the LGE. The LVEF correlated well with the FTc (r = 0.840) and DLSc (r = 0.760). Both techniques had excellent reproducibility, with high intra- (FTc = 0.980, DLSc = 1.000) and inter-observer (FTc = 0.970, DLSc = 0.980) correlation. There was correlation between the LV DLSc/FTc and LVEF in the patients with acute myocarditis according to the CMRd and CMRf.
本研究旨在探讨急性心肌炎患者诊断性心脏磁共振成像（CMRd）和随访性心脏磁共振成像（CMRf）中左心室（LV）心肌特征追踪（FT）与基于深度学习的应变（DLS）分析之间的相关性。这项回顾性研究纳入了17例急性心肌炎患者和20名健康对照者。CMRd在症状出现后14天内进行，而CMRf在事件发生至少2个月后进行。分析了整体圆周FT（FTc）和整体圆周DLS（DLSc）。连续变量采用配对t检验或Wilcoxon检验进行比较，而Pearson检验或Spearman检验用于评估连续变量之间的相关性。CMRd和CMRf之间的时间间隔为5个月[3 - 11]。左心室射血分数（LVEF）分别为55±6%和59±4%，p = 0.008，并且94.1%的患者在CMRd上显示晚期钆增强（LGE）和心肌水肿。与对照组相比，观察到FTc（-16.1±2.2%对-18.9±1.9%，p = 0.001）和DLSc（-38.1±5.2%对-41.3±4.5%，p = 0.015）显著降低。在CMRd和CMRf之间发现FTc（-16.1±2.2对-17.5±1.9%，p = 0.016）和DLSc（-38.1±5.2对-39.8±3.9%，p = 0.049）有显著增加，且与LGE无关。LVEF与FTc（r = 0.840）和DLSc（r = 0.760）相关性良好。两种技术都具有出色的可重复性，观察者内（FTc = 0.980，DLSc = 1.000）和观察者间（FTc = 0.970，DLSc = 0.980）相关性都很高。根据CMRd和CMRf，急性心肌炎患者的左心室DLSc/FTc与LVEF之间存在相关性。
