Goodman R M, Yergin B M, Sackner M A
Chest. 1978 Dec;74(6):615-8. doi: 10.1378/chest.74.6.615.
The effects of S-carboxymethylcysteine on tracheal mucus velocity were assessed in a double blind crossover study between 2 grams S-carboxymethylcysteine and placebo. Subjects included six healthy non-smokers, eight smokers with small airway disease and chronic simple bronchitis, and eight subjects with chronic obstructive bronchitis. Tracheal mucus velocity was measured prior to and two and three hours after each subject had ingested S-carboxymethylcysteine or placebo. No significant change in tracheal mucus velocity occurred after placebo or S-carboxymethylcysteine in any of the groups, indicating that the drug has no acute effect on mucus transport.
在一项双盲交叉研究中，评估了S-羧甲基半胱氨酸对气管黏液速度的影响，该研究对比了2克S-羧甲基半胱氨酸和安慰剂的效果。受试者包括6名健康非吸烟者、8名患有小气道疾病和慢性单纯性支气管炎的吸烟者，以及8名慢性阻塞性支气管炎患者。在每位受试者摄入S-羧甲基半胱氨酸或安慰剂之前、之后两小时和三小时测量气管黏液速度。在任何一组中，安慰剂或S-羧甲基半胱氨酸摄入后气管黏液速度均未发生显著变化，这表明该药物对黏液运输没有急性作用。
