• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

智能软汗传感器用于医疗保健的同步监测和安全预警。

Intelligent Soft Sweat Sensors for the Simultaneous Healthcare Monitoring and Safety Warning.

机构信息

Department of Biomedical Engineering, City University of Hong Kong, Kowloong Tong, Hong Kong, 999077, P. R. China.

Hong Kong Center for Cerebra-Cardiovascular Health Engineering, Hong Kong Science Park, New Territories, Hong Kong, 999077, P. R. China.

出版信息

Adv Healthc Mater. 2023 Jun;12(15):e2202846. doi: 10.1002/adhm.202202846. Epub 2023 Mar 1.

DOI:10.1002/adhm.202202846
PMID:36773301
Abstract

Intelligent monitoring human physiological information in real time raises the demand for skin-integrated electronics, as which is a flexible format and can be mounted onto the curved human skin for noninvasive healthcare monitoring. The biofluid such as sweat from skin contains abundant biomarkers reflecting body health conditions. Here, a skin-integrated sweat monitor with six biosensors embedded for the detection of NH , Na , glucose, pH, skin impedance, and surface temperature is described, which could decode the information in the fresh sweat generated during exercising. Furthermore, the system also includes an innovative safety warning mechanism, which is based on a miniaturized actuator to provide mechanical stimuli, and coupled with six changeable colors light emitting diodes corresponding to the six biosensors for providing simultaneous safety alarming to users. The self-developed microfluidics system with a hydrophilic surface allows to enhance the sweat collection rate. Meanwhile, microfluidic filters can reduce the interruption of skin debris during biosignal monitoring. These state-of-art biosensors can real-time monitor health related signals with excellent linearity and specificity. The skin-integrated sweat monitor system exhibits a great potential in human healthcare monitoring and medical treatment.

摘要

实时智能监测人体生理信息对皮肤集成电子提出了需求,因为它是一种灵活的形式,可以安装在人体曲面上进行非侵入性医疗保健监测。皮肤产生的生物流体(如汗液)中含有丰富的反映身体健康状况的生物标志物。在这里,描述了一种具有嵌入式六个生物传感器的皮肤集成汗液监测器,用于检测 NH 3 、Na + 、葡萄糖、pH 值、皮肤阻抗和表面温度,它可以解码在运动过程中产生的新鲜汗液中的信息。此外,该系统还包括一个创新的安全警告机制,它基于一个微型致动器提供机械刺激,并与六个可更换颜色的发光二极管耦合,对应于六个生物传感器,为用户提供同时的安全报警。具有亲水表面的自开发微流控系统可以提高汗液采集率。同时,微流控过滤器可以减少生物信号监测过程中皮肤碎片的干扰。这些最先进的生物传感器可以实时监测与健康相关的信号,具有优异的线性度和特异性。皮肤集成汗液监测系统在人体健康监测和医疗方面具有巨大的潜力。

相似文献

1
Intelligent Soft Sweat Sensors for the Simultaneous Healthcare Monitoring and Safety Warning.智能软汗传感器用于医疗保健的同步监测和安全预警。
Adv Healthc Mater. 2023 Jun;12(15):e2202846. doi: 10.1002/adhm.202202846. Epub 2023 Mar 1.
2
Flexible Electronics toward Wearable Sensing.柔性电子学:走向可穿戴传感
Acc Chem Res. 2019 Mar 19;52(3):523-533. doi: 10.1021/acs.accounts.8b00500. Epub 2019 Feb 15.
3
Wearable soft electrochemical microfluidic device integrated with iontophoresis for sweat biosensing.可穿戴式软电化学微流控装置与电渗析集成用于汗液生物传感。
Anal Bioanal Chem. 2022 Jul;414(18):5411-5421. doi: 10.1007/s00216-021-03865-9. Epub 2022 Jan 11.
4
Flexible and printable integrated biosensors for monitoring sweat and skin condition.用于监测汗液和皮肤状况的柔性可打印集成生物传感器。
Anal Biochem. 2023 Jan 15;661:114985. doi: 10.1016/j.ab.2022.114985. Epub 2022 Nov 19.
5
A Flexible Microfluidic Chip-Based Universal Fully Integrated Nanoelectronic System with Point-of-Care Raw Sweat, Tears, or Saliva Glucose Monitoring for Potential Noninvasive Glucose Management.一种灵活的基于微流控芯片的通用全集成纳米电子系统,可用于现场原始汗液、眼泪或唾液葡萄糖监测,实现潜在的无创葡萄糖管理。
Anal Chem. 2022 Jan 25;94(3):1890-1900. doi: 10.1021/acs.analchem.1c05174. Epub 2022 Jan 10.
6
Three-Dimensional Integrated Ultra-Low-Volume Passive Microfluidics with Ion-Sensitive Field-Effect Transistors for Multiparameter Wearable Sweat Analyzers.基于离子敏感场效应晶体管的三维集成超低体积微流控芯片用于多参数可穿戴汗液分析器。
ACS Nano. 2018 Dec 26;12(12):12646-12656. doi: 10.1021/acsnano.8b07413. Epub 2018 Dec 14.
7
Epidermal Microfluidic Electrochemical Detection System: Enhanced Sweat Sampling and Metabolite Detection.表皮微流控电化学检测系统:增强的汗液采样和代谢物检测。
ACS Sens. 2017 Dec 22;2(12):1860-1868. doi: 10.1021/acssensors.7b00729. Epub 2017 Dec 1.
8
Printed microfluidic sweat sensing platform for cortisol and glucose detection.用于皮质醇和葡萄糖检测的印刷微流控汗液感应平台。
Lab Chip. 2021 Dec 21;22(1):156-169. doi: 10.1039/d1lc00633a.
9
Stretchable Sweat-Activated Battery in Skin-Integrated Electronics for Continuous Wireless Sweat Monitoring.可拉伸的汗液激活电池,用于皮肤集成电子设备,实现连续的无线汗液监测。
Adv Sci (Weinh). 2022 Mar;9(9):e2104635. doi: 10.1002/advs.202104635. Epub 2022 Jan 28.
10
A Skin-Interfaced, Miniaturized Microfluidic Analysis and Delivery System for Colorimetric Measurements of Nutrients in Sweat and Supply of Vitamins Through the Skin.一种用于通过皮肤进行汗液中营养物质的比色测量和维生素供应的皮肤界面、微型化微流控分析和输送系统。
Adv Sci (Weinh). 2022 Jan;9(2):e2103331. doi: 10.1002/advs.202103331. Epub 2021 Nov 7.

引用本文的文献

1
Wearable Electrochemical Glucose Sensors for Fluid Monitoring: Advances and Challenges in Non-Invasive and Minimally Invasive Technologies.用于液体监测的可穿戴式电化学葡萄糖传感器:非侵入性和微创技术的进展与挑战
Biosensors (Basel). 2025 May 12;15(5):309. doi: 10.3390/bios15050309.
2
Miniaturized, portable gustation interfaces for VR/AR/MR.用于 VR/AR/MR 的微型、便携式味觉接口。
Proc Natl Acad Sci U S A. 2024 Dec 3;121(49):e2412116121. doi: 10.1073/pnas.2412116121. Epub 2024 Nov 25.
3
Development and Application of IoT Monitoring Systems for Typical Large Amusement Facilities.
典型大型游乐设施物联网监测系统的开发与应用
Sensors (Basel). 2024 Jul 9;24(14):4433. doi: 10.3390/s24144433.
4
[Application of electronic skin in healthcare and virtual reality].[电子皮肤在医疗保健和虚拟现实中的应用]
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2023 Dec 25;40(6):1062-1070. doi: 10.7507/1001-5515.202210035.