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激光治疗婴幼儿血管瘤。

Laser treatment of infantile hemangioma.

机构信息

Department of Dermatology, Rambam Health Care Campus, Haifa, Israel.

Bruce Rappaport Faculty of Medicine, Technion Institute of Technology, Haifa, Israel.

出版信息

J Cosmet Dermatol. 2023 Jun;22 Suppl 2:1-7. doi: 10.1111/jocd.15671. Epub 2023 Feb 12.

DOI:10.1111/jocd.15671
PMID:36774645
Abstract

BACK GROUNDS AND OBJECTIVE

Infantile hemangiomas (IH) are common benign tumors of infancy. Most IH either involute spontaneously or respond to treatment with systemic Beta- blockers, but unfortunately not in all cases. In poor responses or in cases of contra indications for pharmacological treatment, laser treatment poses a very good solution.

METHODS

As a search strategy and study selection we searched the MEDLINE database via PubMed starting 1982 to June 2022 using a key terms related to interventions for IH (e.g., infantile hemangioma, laser, Beta blockers).

RESULTS

In this article, we reviewed the published data regarding the use of energy-based devices in treatment of children with IH, and noted our experience over the course of treating dozens of cases over the years.

CONCLUSION

There are many laser systems used for the treatment of hemangioma and vascular tumors. These laser systems are of different wavelengths and penetration depths, however, they operate by similar mechanisms and in some cases two or more lasers can be applied during the course of treating these lesions.

摘要

背景和目的

婴儿血管瘤(IH)是一种常见的婴儿良性肿瘤。大多数 IH 会自发消退或对全身β受体阻滞剂治疗有反应,但并非所有病例都如此。在反应不佳或存在药物治疗禁忌症的情况下,激光治疗是一个非常好的解决方案。

方法

作为搜索策略和研究选择,我们通过 PubMed 在 MEDLINE 数据库中进行了搜索,检索时间从 1982 年开始至 2022 年 6 月,使用了与 IH 干预措施相关的关键词(例如,婴儿血管瘤、激光、β受体阻滞剂)。

结果

在本文中,我们回顾了关于能量设备在儿童 IH 治疗中的应用的已发表数据,并记录了多年来治疗数十例病例的经验。

结论

有许多用于治疗血管瘤和血管肿瘤的激光系统。这些激光系统的波长和穿透深度不同,但它们的工作原理相似,在某些情况下,两种或更多种激光可以在治疗这些病变的过程中应用。

相似文献

1
Laser treatment of infantile hemangioma.激光治疗婴幼儿血管瘤。
J Cosmet Dermatol. 2023 Jun;22 Suppl 2:1-7. doi: 10.1111/jocd.15671. Epub 2023 Feb 12.
2
Nd:YAG and pulsed dye laser therapy in infantile haemangiomas: a retrospective analysis of 271 treated haemangiomas in 149 children.Nd:YAG 和脉冲染料激光治疗婴幼儿血管瘤:271 例 149 例患儿治疗后血管瘤的回顾性分析。
J Eur Acad Dermatol Venereol. 2017 Aug;31(8):1372-1379. doi: 10.1111/jdv.14074. Epub 2017 Jan 23.
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Laser treatment of infantile hemangioma: A systematic review.婴儿血管瘤的激光治疗:一项系统评价。
Lasers Surg Med. 2016 Mar;48(3):221-33. doi: 10.1002/lsm.22455. Epub 2015 Dec 29.
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Propranolol is more effective than pulsed dye laser and cryosurgery for infantile hemangiomas.普萘洛尔治疗婴儿血管瘤比脉冲染料激光和冷冻疗法更有效。
Eur J Pediatr. 2013 Nov;172(11):1521-6. doi: 10.1007/s00431-013-2075-7. Epub 2013 Jun 29.
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Treatment of infantile hemangiomas with beta-blockers: a review.β受体阻滞剂治疗婴幼儿血管瘤:综述
Skin Therapy Lett. 2013 Sep-Oct;18(6):5-7.
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Nd:YAG 1064-nm laser for residual infantile hemangioma after propranolol treatment.钕:钇铝石榴石 1064nm 激光治疗普萘洛尔治疗后残留婴儿血管瘤。
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Pulsed dye laser therapy for infantile hemangiomas: a systemic review and meta-analysis.脉冲染料激光治疗婴幼儿血管瘤:系统评价和荟萃分析。
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Surgical treatment outcomes of infantile hemangioma in children: Does prior medical treatment matter.儿童婴幼儿血管瘤的手术治疗结果:先前的药物治疗有影响吗?
Pediatr Dermatol. 2018 Nov;35(6):e418-e419. doi: 10.1111/pde.13658. Epub 2018 Sep 6.
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Clinical Outcomes of Small Infantile Hemangiomas Treated With Pulsed Dye Laser.脉冲染料激光治疗小婴儿血管瘤的临床疗效。
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[The advance of β-blockers in the treatment of infantile hemangiomas].[β受体阻滞剂在婴幼儿血管瘤治疗中的进展]
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A novel therapeutic approach to hemangiomas: Combining photothermal therapy and ferroptosis in a microneedle delivery system.一种治疗血管瘤的新方法:在微针递送系统中结合光热疗法和铁死亡。
Mater Today Bio. 2025 Apr 9;32:101748. doi: 10.1016/j.mtbio.2025.101748. eCollection 2025 Jun.
2
Cryocarboxy Surgery: A New Armamentarium in the Treatment of Infantile Hemangiomas of the Lips.冷冻消融手术:治疗唇部婴幼儿血管瘤的一种新手段
J Maxillofac Oral Surg. 2024 Oct;23(5):1282-1288. doi: 10.1007/s12663-024-02138-z. Epub 2024 Jun 1.
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Infantile hemangiomas: a dermatologist's perspective.
婴幼儿血管瘤:皮肤科医生的视角。
Eur J Pediatr. 2024 Oct;183(10):4159-4168. doi: 10.1007/s00431-024-05655-8. Epub 2024 Jul 25.
4
Revealing the mechanism of 755-nm long-pulsed alexandrite laser in inhibiting infantile hemangioma endothelial cells through transcriptome sequencing.通过转录组测序揭示 755nm 长脉冲翠绿宝石激光抑制婴幼儿血管瘤内皮细胞的机制。
Lasers Med Sci. 2024 Jan 18;39(1):37. doi: 10.1007/s10103-023-03967-z.