Ishikawa Kiyoshi, Uchida Toshiki
Department of Rehabilitation, Aichi Medical College.
Department of Hematology and Oncology, Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital.
Rinsho Ketsueki. 2023;64(1):66-68. doi: 10.11406/rinketsu.64.66.
Cyclic thrombocytopenia (CTP) is characterized by periodic platelet count fluctuations and is commonly misdiagnosed as immune thrombocytopenia (ITP) because of their similar clinical characteristics. Here, we present the case of a 74-year-old man with CTP diagnosed by weekly platelet count measurements. The patient initially developed mild bleeding symptoms with a platelet count of 0.8×10/µl. Bone marrow biopsy exhibited reduced megakaryocyte counts, an atypical characteristic of ITP. Weekly follow-up of platelet counts demonstrated an apparent cyclic pattern, resulting in CTP diagnosis. Regular platelet count measurements can help diagnose CTP in thrombocytopenia.
周期性血小板减少症（CTP）的特征是血小板计数呈周期性波动，由于其临床特征相似，常被误诊为免疫性血小板减少症（ITP）。在此，我们报告一例74岁男性经每周血小板计数测量确诊为CTP的病例。患者最初出现轻度出血症状，血小板计数为0.8×10/µl。骨髓活检显示巨核细胞计数减少，这是ITP的非典型特征。每周对血小板计数进行随访显示出明显的周期性模式，从而确诊为CTP。定期测量血小板计数有助于诊断血小板减少症中的CTP。
