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通过定期血小板计数测量诊断的周期性血小板减少症

[Cyclic thrombocytopenia diagnosed by periodic platelet count measurements].

作者信息

Ishikawa Kiyoshi, Uchida Toshiki

机构信息

Department of Rehabilitation, Aichi Medical College.

Department of Hematology and Oncology, Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital.

出版信息

Rinsho Ketsueki. 2023;64(1):66-68. doi: 10.11406/rinketsu.64.66.

Abstract

Cyclic thrombocytopenia (CTP) is characterized by periodic platelet count fluctuations and is commonly misdiagnosed as immune thrombocytopenia (ITP) because of their similar clinical characteristics. Here, we present the case of a 74-year-old man with CTP diagnosed by weekly platelet count measurements. The patient initially developed mild bleeding symptoms with a platelet count of 0.8×10/µl. Bone marrow biopsy exhibited reduced megakaryocyte counts, an atypical characteristic of ITP. Weekly follow-up of platelet counts demonstrated an apparent cyclic pattern, resulting in CTP diagnosis. Regular platelet count measurements can help diagnose CTP in thrombocytopenia.

摘要

周期性血小板减少症(CTP)的特征是血小板计数呈周期性波动,由于其临床特征相似,常被误诊为免疫性血小板减少症(ITP)。在此,我们报告一例74岁男性经每周血小板计数测量确诊为CTP的病例。患者最初出现轻度出血症状,血小板计数为0.8×10/µl。骨髓活检显示巨核细胞计数减少,这是ITP的非典型特征。每周对血小板计数进行随访显示出明显的周期性模式,从而确诊为CTP。定期测量血小板计数有助于诊断血小板减少症中的CTP。

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