Division of Family Medicine, En Chu Kong Hospital, New Taipei City, Taiwan; Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan; Department of Leisure Services Management, Chaoyang University of Technology, Taichung, Taiwan.
Division of Metabolism and Endocrinology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
J Formos Med Assoc. 2023;122 Suppl 1:S14-S20. doi: 10.1016/j.jfma.2023.01.013. Epub 2023 Feb 10.
Postmenopausal women are at significant risk for osteoporotic fractures due to their rapid bone loss. Half of all postmenopausal women will get an osteoporosis-related fracture over their lifetime, with 25% developing a spine deformity and 15% developing a hip fracture. By 2050, more than half of all osteoporotic fractures will occur in Asia, with postmenopausal women being the most susceptible. Early management can halt or even reverse the progression of osteoporosis. Consequently, on October 31, 2020, the Taiwanese Osteoporosis Association hosted the Asia-Pacific (AP) Postmenopausal Osteoporotic Fracture Prevention (POFP) consensus meeting, which was supported by the Asian Federation of Osteoporosis Societies (AFOS) and the Asia Pacific Osteoporosis Foundation (APOF). International and domestic experts developed ten applicable statements for the prevention of osteoporotic fractures in postmenopausal women with low bone mass or osteoporosis but no fragility fractures in the AP region. The experts advocated, for example, that postmenopausal women with a high fracture risk be reimbursed for pharmaceutical therapy to prevent osteoporotic fractures. More clinical experience and data are required to modify intervention tactics.
绝经后妇女由于快速骨质流失，骨质疏松性骨折的风险显著增加。在她们的一生中，有一半的人会发生骨质疏松相关的骨折，其中 25%的人会出现脊柱畸形，15%的人会出现髋部骨折。到 2050 年，亚洲将发生超过一半的骨质疏松性骨折，绝经后妇女是最易受影响的人群。早期管理可以阻止甚至逆转骨质疏松症的进展。因此，2020 年 10 月 31 日，台湾骨质疏松症协会主办了亚太地区（AP）绝经后骨质疏松性骨折预防（POFP）共识会议，该会议得到亚洲骨质疏松症学会联合会（AFOS）和亚太骨质疏松基金会（APOF）的支持。国际和国内专家为 AP 地区低骨量或骨质疏松但无脆性骨折的绝经后妇女制定了 10 条适用于预防骨质疏松性骨折的可应用声明。专家们主张，对高骨折风险的绝经后妇女进行药物治疗以预防骨质疏松性骨折应给予报销。需要更多的临床经验和数据来修改干预策略。
