Gong Maofeng, Fu Guanqi, Liu Zhengli, Zhou Yangyi, Zhao Boxiang, Kong Jie, He Xu, Gu Jianping
Department of Interventional and Vascular Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, P.R. China.
Digit Health. 2023 Feb 7;9:20552076231154691. doi: 10.1177/20552076231154691. eCollection 2023 Jan-Dec.
The objective of this study was to investigate the risk of acute kidney injury in elderly patients compared with nonelderly patients undergoing AngioJet rheolytic thrombectomy for treatment of acute deep vein thrombosis.
A retrospective review of all patients who underwent AngioJet rheolytic thrombectomy for the treatment of acute deep vein thrombosis between November 1, 2014 and August 1, 2022 was conducted. Their baseline demographics, comorbidities, clinical characteristics, procedural details, and postoperative course were reviewed.
A total of 105 eligible patients were reviewed; 45 patients were in the elderly group, and 60 were in the nonelderly group. Except for age ( 0.001), no significant differences regarding demographics were detected ( >0.05). Transient macroscopic hemoglobinuria occurred in all patients during the first 24 h post-AngioJet rheolytic thrombectomy. The overall morbidity of acute kidney injury in the two groups was 11.4%, and the nonelderly group had a similar rate of acute kidney injury (8.3%) to the elderly group (15.6%). None of the 12 patients progressed to dialysis within the postoperative period, and the mean acute kidney injury recovery time of the elderly group was 5.86 ± 1.57 days, which was longer than the 3.60 ± .89 days of the nonelderly group ( = 0.017).
The use of AngioJet rheolytic thrombectomy for the treatment of patients with acute deep vein thrombosis is associated with a potential risk of acute kidney injury, which seems to have a comparable rate in elderly and nonelderly patients. acute kidney injury in the elderly group tends to need a longer recovery time, which requires postoperative vigilance for this population.
本研究的目的是调查与接受AngioJet血栓消融术治疗急性深静脉血栓形成的非老年患者相比，老年患者发生急性肾损伤的风险。
对2014年11月1日至2022年8月1日期间接受AngioJet血栓消融术治疗急性深静脉血栓形成的所有患者进行回顾性研究。回顾了他们的基线人口统计学、合并症、临床特征、手术细节和术后病程。
共纳入105例符合条件的患者；老年组45例，非老年组60例。除年龄（P<0.001）外，在人口统计学方面未发现显著差异（P>0.05）。所有患者在AngioJet血栓消融术后24小时内均出现短暂性肉眼血红蛋白尿。两组急性肾损伤的总体发病率为11.4%，非老年组急性肾损伤发生率（8.3%）与老年组（15.6%）相似。12例患者术后均未进展为透析，老年组急性肾损伤平均恢复时间为5.86±1.57天，长于非老年组的3.60±0.89天（P=0.017）。
使用AngioJet血栓消融术治疗急性深静脉血栓形成患者与急性肾损伤的潜在风险相关，老年患者和非老年患者的发生率似乎相当。老年组急性肾损伤往往需要更长的恢复时间，这需要对该人群进行术后密切观察。
