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克罗恩病诊断时表现为脓肿与蜂窝织炎的儿童的长期预后相似。

Similar Long-Term Outcomes in Children Presenting With Abscess vs Phlegmon at Diagnosis of Crohn Disease.

作者信息

Fondell Andrew W, Mosha Maua H, Maltz Ross M, Boyle Brendan M, Niklinska-Schirtz Barbara Joanna, Kugathasan Subra, Gibson Meghan E, Shapiro Jason M, Rosenheck Sarah M, Langseder Annette L, Kennedy Mary C, Rosh Joel R, Hyams Jeffrey S

机构信息

Division of Digestive Diseases, Hepatology, and Nutrition, Connecticut Children's, Hartford, Connecticut, USA.

Division of Pediatric Gastroenterology, Hepatology and Nutrition, Nationwide Children's Hospital, Columbus, Ohio, USA.

出版信息

Crohns Colitis 360. 2020 Jul 20;2(3):otaa060. doi: 10.1093/crocol/otaa060. eCollection 2020 Jul.

DOI:10.1093/crocol/otaa060
PMID:36776501
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9802424/
Abstract

BACKGROUND

Limited data are available for long-term outcomes of pediatric patients with abdominal abscess or phlegmon at diagnosis of Crohn disease.

METHODS

We performed a retrospective chart review of such children over a recent 6-year period at 5 pediatric inflammatory bowel diseases.

RESULTS

Fifty-two patients (mean age 15.9 ± 1.8 years) were reviewed. Thirty-six had an abscess and 27 (75%) required resectional therapy compared to 16 with phlegmon which 10 (63%) requiring surgery. Overall (37/52) 71% had surgery which was performed within 6 months in 32 (86%).

CONCLUSIONS

A similar high surgical rate exists whether pediatric patients with Crohn disease present with abscess or phlegmon.

摘要

背景

关于克罗恩病诊断时患有腹部脓肿或蜂窝织炎的儿科患者的长期预后,可用数据有限。

方法

我们对5家儿科炎症性肠病中心最近6年的此类儿童进行了回顾性病历审查。

结果

共审查了52例患者(平均年龄15.9±1.8岁)。36例有脓肿,其中27例(75%)需要进行切除治疗;16例有蜂窝织炎,其中10例(63%)需要手术。总体而言,52例中有37例(71%)接受了手术,其中32例(86%)在6个月内进行了手术。

结论

克罗恩病的儿科患者无论是出现脓肿还是蜂窝织炎,手术率都同样高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10d0/9802424/2b7549e05c9a/otaa060f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10d0/9802424/df79090655b9/otaa060f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10d0/9802424/2b7549e05c9a/otaa060f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10d0/9802424/df79090655b9/otaa060f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10d0/9802424/2b7549e05c9a/otaa060f0002.jpg

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本文引用的文献

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ECCO-ESGAR Guideline for Diagnostic Assessment in IBD Part 2: IBD scores and general principles and technical aspects.欧洲克罗恩病和结肠炎组织-欧洲胃肠内镜学会炎症性肠病诊断评估指南第2部分:炎症性肠病评分及一般原则和技术方面
J Crohns Colitis. 2019 Mar 26;13(3):273-284. doi: 10.1093/ecco-jcc/jjy114.
2
ECCO-ESGAR Guideline for Diagnostic Assessment in IBD Part 1: Initial diagnosis, monitoring of known IBD, detection of complications.欧洲克罗恩病和结肠炎组织(ECCO)与欧洲胃肠内镜学会(ESGAR)炎症性肠病诊断评估指南 第1部分:初始诊断、已知炎症性肠病的监测、并发症的检测
J Crohns Colitis. 2019 Feb 1;13(2):144-164. doi: 10.1093/ecco-jcc/jjy113.
3
The Management of Intestinal Penetrating Crohn's Disease.
肠穿透性克罗恩病的管理。
Inflamm Bowel Dis. 2018 Mar 19;24(4):752-765. doi: 10.1093/ibd/izx108.
4
Natural disease course of Crohn's disease during the first 5 years after diagnosis in a European population-based inception cohort: an Epi-IBD study.在欧洲基于人群的发病队列中,诊断后 5 年内克罗恩病的自然病程:一项 Epi-IBD 研究。
Gut. 2019 Mar;68(3):423-433. doi: 10.1136/gutjnl-2017-315568. Epub 2018 Jan 23.
5
Penetrating Crohn disease: does it occur in the absence of stricturing disease?穿透性克罗恩病:是否在无狭窄性疾病的情况下发生?
Abdom Radiol (NY). 2018 Jul;43(7):1583-1589. doi: 10.1007/s00261-017-1398-7.
6
Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study.新诊断为克罗恩病儿童复杂疾病病程的预测:一项多中心发病队列研究。
Lancet. 2017 Apr 29;389(10080):1710-1718. doi: 10.1016/S0140-6736(17)30317-3. Epub 2017 Mar 2.
7
Role of percutaneous abscess drainage in the management of young patients with Crohn disease.经皮脓肿引流在年轻克罗恩病患者管理中的作用。
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Management of intra-abdominal abscesses in children with Crohn's disease: a 12-year, retrospective single-center review.克罗恩病患儿腹腔内脓肿的管理:一项为期12年的回顾性单中心研究。
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