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扩大大乳房或下垂乳房女性保留乳头乳房切除术的适应证:分期重建结果

Expanding Candidacy for Nipple-sparing Mastectomy in Women with Large or Ptotic Breasts: Staged Reconstruction Outcomes.

作者信息

Barnes Laura L, Foster Rob, Mukhtar Rita A, Esserman Laura J, Ewing Cheryl, Alvarado Michael, Wong Jasmine, Piper Merisa

机构信息

Division of Plastic and Reconstructive Surgery, University of California, San Francisco, Calif.

Division of Breast Care Surgery, University of California, San Francisco, Calif.

出版信息

Plast Reconstr Surg Glob Open. 2023 Jan 25;11(1):e4767. doi: 10.1097/GOX.0000000000004767. eCollection 2023 Jan.

Abstract

UNLABELLED

Development of the nipple-sparing mastectomy (NSM) technique has dramatically improved breast reconstruction, and preservation of the nipple-areolar complex (NAC) positively influences patient satisfaction. However, women with large, ptotic breasts have historically not been candidates for NAC preservation due to impaired perfusion of the NAC leading to NAC loss. Although reduction mammoplasty has been reported as a strategy to increase candidacy for NSM, success rates and surgical outcomes for this staged approach are not well described in heterogeneous clinical scenarios.

METHODS

We performed a retrospective chart review of all patients who underwent reduction mammoplasty followed by NSM at our institution between January 2014 and September 2020. Clinical and surgical characteristics were collected. All surgical complications, including NAC loss rates, were analyzed.

RESULTS

Forty-one patients (74 breasts) underwent staged NSM during the defined time period. The average time between breast reduction mammoplasty and NSM was 213 days. Overall, 94.6% of NSM resulted in successful nipple preservation. There was no significant difference in the time interval from breast reduction mammoplasty to NSM between patients who had NAC loss (208 days) and those who did not (213 days, = 0.87). Increasing age was significantly associated with risk of NAC loss ( = 0.002) in our cohort.

CONCLUSIONS

In women with breast ptosis (which precludes safe NSM), it is possible to first offer reduction mammoplasty to preserve the NAC for future NSM. Our data suggest that 3 months between staged procedures is a safe time frame.

摘要

未标注

保留乳头的乳房切除术(NSM)技术的发展极大地改善了乳房重建,乳头乳晕复合体(NAC)的保留对患者满意度有积极影响。然而,由于NAC灌注受损导致NAC丢失,乳房较大且下垂的女性历来不是保留NAC的合适人选。尽管有报道称乳房缩小成形术是增加NSM候选资格的一种策略,但在异质性临床场景中,这种分期方法的成功率和手术结果并未得到很好的描述。

方法

我们对2014年1月至2020年9月期间在本机构接受乳房缩小成形术然后进行NSM的所有患者进行了回顾性病历审查。收集了临床和手术特征。分析了所有手术并发症,包括NAC丢失率。

结果

在规定时间段内,41例患者(74个乳房)接受了分期NSM。乳房缩小成形术和NSM之间的平均时间为213天。总体而言,94.6%的NSM成功保留了乳头。发生NAC丢失的患者(208天)与未发生NAC丢失的患者(213天,P = 0.87)从乳房缩小成形术到NSM的时间间隔无显著差异。在我们的队列中,年龄增加与NAC丢失风险显著相关(P = 0.002)。

结论

对于乳房下垂(排除安全的NSM)的女性,可以首先进行乳房缩小成形术以保留NAC,以便未来进行NSM。我们的数据表明,分期手术之间3个月的时间框架是安全的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1de7/9911193/df0c4b4f6da9/gox-11-e4767-g001.jpg

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