疫苗诱导的血栓性血小板减少症继发急性肢体缺血
Acute limb ischemia secondary to vaccine-induced thrombotic thrombocytopenia.
作者信息
Xie Bowen, Semaan Dana B, Sridharan Natalie D, Eslami Mohammad H, Go Catherine
机构信息
Division of Vascular Surgery, UPMC, Pittsburgh, PA.
出版信息
Ann Vasc Surg Brief Rep Innov. 2023 Mar;3(1). doi: 10.1016/j.avsurg.2022.100153. Epub 2022 Dec 23.
Abstract
Vaccine-associated thrombosis has previously been described in patients presenting with cerebral sinus thrombosis, deep venous thrombosis/pulmonary embolism, or mesenteric venous thrombosis. Only recently has arterial thrombosis gained attention. A new entity known as vaccine-induced thrombotic thrombocytopenia (VITT) has been associated with the coronavirus disease of 2019 (COVID-19) vaccines produced by AstraZeneca and Johnson & Johnson. We describe a case series of three patients who presented with acute limb ischemia with vaccine-associated arterial occlusions, one of whom was diagnosed with VITT.
摘要
疫苗相关血栓形成此前已在出现脑窦血栓形成、深静脉血栓形成/肺栓塞或肠系膜静脉血栓形成的患者中有所描述。直到最近，动脉血栓形成才受到关注。一种名为疫苗诱导的血栓性血小板减少症（VITT）的新病症已与阿斯利康和强生公司生产的2019冠状病毒病（COVID-19）疫苗相关联。我们描述了一组三例因疫苗相关动脉闭塞而出现急性肢体缺血的患者病例系列，其中一例被诊断为VITT。
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本文引用的文献
1
New-onset autoimmune phenomena post-COVID-19 vaccination.接种 COVID-19 疫苗后出现的新自身免疫现象。
Immunology. 2022 Apr;165(4):386-401. doi: 10.1111/imm.13443. Epub 2022 Jan 7.
2
VITT and Second Doses of Covid-19 Vaccine.疫苗诱导的免疫性血小板减少症（VITT）与新冠病毒疾病-19疫苗第二剂
N Engl J Med. 2022 Jan 6;386(1):95. doi: 10.1056/NEJMc2118507. Epub 2021 Dec 22.
3
COVID 19 vaccine in patients of hypercoagulable disorders: a clinical perspective.COVID-19 疫苗在高凝状态患者中的应用：临床视角。
Horm Mol Biol Clin Investig. 2021 Nov 17;43(1):89-96. doi: 10.1515/hmbci-2021-0037.
4
The safety profile of COVID-19 vaccinations in the United States.美国 COVID-19 疫苗的安全性概况。
Am J Infect Control. 2022 Jan;50(1):15-19. doi: 10.1016/j.ajic.2021.10.015. Epub 2021 Oct 23.
5
Liver graft outcomes from donors with vaccine induced thrombosis and thrombocytopenia (VITT): United Kingdom multicenter experience.疫苗诱导的血栓形成和血小板减少症（VITT）供体的肝移植结果：英国多中心经验
Am J Transplant. 2022 Mar;22(3):996-998. doi: 10.1111/ajt.16869. Epub 2021 Oct 29.
6
Clinical Features of Vaccine-Induced Immune Thrombocytopenia and Thrombosis.疫苗诱导的免疫性血小板减少症和血栓形成的临床特征。
N Engl J Med. 2021 Oct 28;385(18):1680-1689. doi: 10.1056/NEJMoa2109908. Epub 2021 Aug 11.
7
Three cases of acute venous thromboembolism in females after vaccination for coronavirus disease 2019.三例女性接种 2019 冠状病毒病疫苗后发生急性静脉血栓栓塞症。
J Vasc Surg Venous Lymphat Disord. 2022 Jan;10(1):14-17. doi: 10.1016/j.jvsv.2021.07.009. Epub 2021 Aug 2.
8
Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know.疫苗诱导的免疫性血栓性血小板减少症：我们已知和未知的。
Blood. 2021 Jul 29;138(4):293-298. doi: 10.1182/blood.2021012152. Epub 2021 Jun 1.
9
Absence of hypercoagulability after nCoV-19 vaccination: An observational pilot study.接种新冠病毒疫苗后无高凝状态：一项观察性初步研究。
Thromb Res. 2021 Sep;205:24-28. doi: 10.1016/j.thromres.2021.06.016. Epub 2021 Jun 25.
10
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