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[卵巢无性细胞瘤——27例临床报告]

[Dysgerminoma of the ovary--a clinical report of 27 patients].

作者信息

Hou Y J, Liu L Y

机构信息

Cancer Hospital, Chinese Academy of Medical Sciences, Beijing.

出版信息

Zhonghua Zhong Liu Za Zhi. 1987 Jul;9(4):311-4.

PMID:3678024
Abstract

Twenty seven patients with dysgerminoma of the ovary were treated in our hospital from 1959 to 1982. 18 of them had no prior treatment and the other 9 had undergone operation and were admitted for recurrence. Among these 18 untreated patients, all were successfully operated. Apart from 4, the others were supplemented by radiotherapy and/or chemotherapy. 17 (94%) were free of disease from 3 to 24 years, only one died of tumor recurrence within 5 years after the initial treatment. The 5 year survival rate was 94%. However, among the 9 recurrent patients, 6 were treated by operation, supplemented by postoperative radiotherapy and/or chemotherapy but only 3 survived for 7, 14 and 15 years respectively without any evidence of disease. The 5 year survival rate was 33%. As those patients who received conservative operation initially gave a high recurrence rate, the authors propose that the patients be treated individually according to the condition of disease. The choice of treatment for the individual patient is discussed.

摘要

1959年至1982年期间,我院共收治27例卵巢无性细胞瘤患者。其中18例未曾接受过治疗,另外9例曾接受手术治疗,此次因复发入院。在这18例未经治疗的患者中,均成功接受了手术。除4例患者外,其余患者均接受了放疗和/或化疗。17例(94%)患者在3至24年期间无疾病复发,仅1例在初始治疗后5年内死于肿瘤复发。5年生存率为94%。然而,在9例复发患者中,6例接受了手术治疗,并在术后接受了放疗和/或化疗,但只有3例分别存活了7年、14年和15年,无任何疾病迹象。5年生存率为33%。由于那些最初接受保守手术的患者复发率较高,作者建议根据疾病情况对患者进行个体化治疗。文中讨论了针对个体患者的治疗选择。

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