Koike Yuya, Kai Ryozo, Abe Ryosuke, Munechika Jiro, Ohgiya Yoshimitsu
Division of Radiology, Department of Radiology, Showa University School of Medicine, Tokyo, Japan.
Department of Interventional Radiology, Saiseikai Yokohamashi Nanbu Hospital, Kanagawa, Japan.
Minim Invasive Ther Allied Technol. 2023 Apr;32(2):81-89. doi: 10.1080/13645706.2023.2174806. Epub 2023 Feb 13.
Percutaneous intradiscal drainage had little established evidence to date. We assessed the outcomes of C-arm cone-beam CT-guided (CBCT-guided) procedures for spondylodiscitis and compare procedures with and without intradiscal drainage.
A retrospective review was conducted on patients who underwent CBCT-guided procedures for spondylodiscitis with fluid collection in the intradiscal space between January 2010 and September 2021. Included patients were divided into two groups: with and without 'intradiscal drainage' (ID and non-ID, respectively).
A total of 87 patients with thoracolumbar discitis (mean age 73.4 ± 12.3 years, 35 females) were included. There was no significant difference in clinical outcomes between groups. Although insignificant, a subgroup analysis of patients with discitis and psoas abscess showed a higher infection control success rate (81% (17/21) vs 58% (7/12), = .23) and faster median C-reactive protein improvement (CRP <3 mg/dL: 12 vs 42 days, = .11, CRP <1 mg/dL: 27 vs 45 days, = .097) of ID than of non-ID.
Findings did not clarify the role of intradiscal drainage when it was indicated in all cases of spondylodiscitis with fluid collection. Future studies with larger sample sizes of selected discitis cases are expected to demonstrate the superiority of intradiscal drainage.
迄今为止,经皮椎间盘内引流术的证据尚不充分。我们评估了C形臂锥形束CT引导下(CBCT引导)治疗脊椎椎间盘炎的手术效果,并比较了有无椎间盘内引流的手术。
对2010年1月至2021年9月期间接受CBCT引导下手术治疗、椎间盘间隙有积液的脊椎椎间盘炎患者进行回顾性研究。纳入患者分为两组:有和无“椎间盘内引流”(分别为ID组和非ID组)。
共纳入87例胸腰椎椎间盘炎患者(平均年龄73.4±12.3岁,女性35例)。两组临床结果无显著差异。虽然不显著,但对患有椎间盘炎和腰大肌脓肿的患者进行的亚组分析显示,ID组的感染控制成功率更高(81%(17/21)对58%(7/12),P = 0.23),C反应蛋白改善中位数更快(C反应蛋白<3mg/dL:12天对42天,P = 0.11,C反应蛋白<1mg/dL:27天对45天,P = 0.097)。
研究结果并未明确在所有伴有积液的脊椎椎间盘炎病例中进行椎间盘内引流的作用。未来对选定椎间盘炎病例进行更大样本量的研究有望证明椎间盘内引流的优势。