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巩膜炎相关眼内炎症与单纯巩膜炎的视觉发病率和结局比较。

Visual Morbidity and Outcomes of Scleritis Associated with Intraocular Inflammation Compared to Isolated Scleritis.

机构信息

Emory Eye Center, Uveitis Service, Emory University School of Medicine, Atlanta, Georgia, USA.

Department of Epidemiology, Emory University School of Medicine, Atlanta, Georgia, USA.

出版信息

Ocul Immunol Inflamm. 2024 Aug;32(6):947-954. doi: 10.1080/09273948.2022.2164726. Epub 2023 Feb 13.

Abstract

PURPOSE

To compare visual outcomes, ocular complications and therapies for patients with scleritis-associated intraocular inflammation (SAI) and patients with isolated scleritis (IS).

RESULTS

A total of 52 patients (36 with SAI and 16 with IS) were reviewed. Mean age (standard deviation) at presentation was 48.4 years old (± 15.4) in the SAI group and 53 years old (± 17.1) in the IS group (p = .37). Visual acuity was worse at presentation and last visit for patients with SAI compared to IS (p = .04). Patients in the SAI group developed greater posterior segment complications than in the IS group (p = .002).

CONCLUSIONS

Scleritis with intraocular inflammation was associated with a higher rate of visual morbidity compared to isolated scleritis. More aggressive management strategies may be needed for patients who present with scleritis associated with inflammation.

摘要

目的

比较巩膜炎相关性眼内炎症(SAI)患者和单纯巩膜炎(IS)患者的视力结果、眼部并发症和治疗方法。

结果

共回顾了 52 名患者(36 名 SAI 和 16 名 IS)。SAI 组的平均年龄(标准差)为 48.4 岁(±15.4),IS 组为 53 岁(±17.1)(p=0.37)。与 IS 相比,SAI 患者的视力在就诊时和最后一次就诊时均较差(p=0.04)。与 IS 相比,SAI 组患者的后节并发症发生率更高(p=0.002)。

结论

与单纯巩膜炎相比,伴眼内炎症的巩膜炎患者的视力受损发生率更高。对于出现巩膜炎相关性炎症的患者,可能需要更积极的治疗策略。

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