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[急性旋毛虫病。一次流行中的193例病例]

[Acute trichinosis. 193 cases in an epidemic].

作者信息

Remig J, Fröscher W

机构信息

Herz- und thoraxchirurgische Abteilung, Johanniter-Kinderklinik, Sankt Augustin.

出版信息

Dtsch Med Wochenschr. 1987 Nov 27;112(48):1855-9. doi: 10.1055/s-2008-1068342.

Abstract

In 1982, an epidemic of acute trichinosis occurred in Bitburg with 402 cases. The acute stage was observed and documented in 193 patients. The first signs of the disease appeared on average 17 days after eating trichina-containing meat. Muscle pain was reported by 85% of patients, lid and/or facial edema by 83%, gastrointestinal complaints by 62%, fever by 60%, flu-like symptoms by 56%, headache by 26%, eye complaints by 19%. Eosinophils were present in the blood of 92%. Trichinella antibodies were demonstrated in 98% of patients examined for them. Interstitial myositis was found in 90% of muscle biopsies (from 162 patients). Serious complications--thrombosis, myocarditis, pneumonia, hepatitis or meningism--occurred in 26 (13.5%) of the 193 patients. Even six months after onset of the disease 43% of patients were still not free of symptoms.

摘要

1982年,比特堡发生急性旋毛虫病疫情,有402例病例。对193例患者的急性期进行了观察和记录。该病的最初症状平均在食用含旋毛虫的肉类17天后出现。85%的患者报告有肌肉疼痛,83%有眼睑和/或面部水肿,62%有胃肠道不适,60%有发热,56%有流感样症状,26%有头痛,19%有眼部不适。92%的患者血液中存在嗜酸性粒细胞。在接受检测的患者中,98%检测出旋毛虫抗体。在90%的肌肉活检(来自162例患者)中发现间质性肌炎。193例患者中有26例(13.5%)出现严重并发症——血栓形成、心肌炎、肺炎、肝炎或脑膜刺激征。即使在疾病发作六个月后,仍有43%的患者症状未消除。

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