Serrano R, Lacasa J, Velázquez J, Ziad F, Aznar R
Enferm Infecc Microbiol Clin. 1989 Oct;7(8):428-31.
After the evaluation of 129 serum samples of persons who had ingested boar sausage infested by Trichinella spiralis, 48 individuals (40 adults and 8 children) with a mean age of 38.8 years were diagnosed of trichinosis. The incubation time was 17 days (range 2 to 44 days). The following clinical features were outstanding: facial and eyelid edema (50%), diffuse limb myalgia (43%), fever (37%), conjunctivitis (25%), headache (16%), and abdominal pain (16%). Remarkably, 33% of the diagnosed patients were asymptomatic. The diagnosis was made by an indirect immunofluorescence technique (IIF), which was considered as positive when the titer was higher than 1/20 after considering seroconversion at the beginning of the disease and after 4-6 weeks. Among laboratory abnormalities there was leukocytosis in 15 patients and eosinophilia in 37. The GOT, GPT and CPK enzymes were only slightly increased in a small proportion of patients (8, 10, and 31%, respectively). Forty patients were treated with thiabendazole, associated or not to corticosteroids, which was well tolerated. Eight patients were not treated. One year after the diagnosis a new laboratory control was undertaken in 43 patients (all asymptomatic). Eosinophilia was still present in 12, and the titers against Trichinella were high in all. However, the percentage of the titer was smaller than at the beginning of the outbreak.
对129份曾食用感染旋毛虫野猪香肠的人的血清样本进行评估后，诊断出48人（40名成人和8名儿童）患有旋毛虫病，平均年龄为38.8岁。潜伏期为17天（范围为2至44天）。以下临床特征较为突出：面部和眼睑水肿（50%）、弥漫性肢体肌痛（43%）、发热（37%）、结膜炎（25%）、头痛（16%）和腹痛（16%）。值得注意的是，33%的确诊患者无症状。诊断采用间接免疫荧光技术（IIF），在考虑疾病初期血清转化以及4至6周后，当滴度高于1/20时被视为阳性。实验室异常情况包括15例白细胞增多和37例嗜酸性粒细胞增多。一小部分患者（分别为8%、10%和31%）的谷草转氨酶、谷丙转氨酶和肌酸磷酸激酶酶仅略有升高。40例患者接受了噻苯达唑治疗，联合或未联合使用皮质类固醇，耐受性良好。8例患者未接受治疗。诊断一年后，对43例患者（均无症状）进行了新的实验室检查。12例患者仍存在嗜酸性粒细胞增多，且所有人针对旋毛虫的滴度都很高。然而，滴度百分比低于疫情爆发初期。
