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用于对抗微生物感染的铋纳米颗粒。

Bismuth nanoparticles against microbial infections.

作者信息

Neamati Foroogh, Kodori Mansoor, Feizabadi Mohammad Mehdi, Abavisani Mohammad, Barani Mohammad, Khaledi Mansoor, Moghadaszadeh Masoud, Azadbakht Mohammad Karim, Zeinali Mojdeh, Fathizadeh Hadis

机构信息

Department of Microbiology & Immunology, Kashan University of Medical Sciences, Kashan, 8713187591, I.R. Iran.

Noncommunicable Diseases Research Center, Bam University of Medical Sciences, Bam, 7661635596, Iran.

出版信息

Nanomedicine (Lond). 2022 Nov;17(27):2109-2122. doi: 10.2217/nnm-2022-0153. Epub 2023 Feb 14.

Abstract

The destructive effect of infectious diseases on human life and the emergence of antibiotic-resistant strains highlight the importance of developing new and appropriate treatment strategies, one of which is the use of metals as therapeutic agents. Bismuth nanoparticles are an example of prominent metal-containing drugs. The therapeutic effects of bismuth-based drugs in the treatment of wounds have been proven. Various laboratory studies have confirmed the antimicrobial effects of bismuth nanoparticles, including the clinical treatment of ulcers caused by . Therefore, considering the performance of this nanoparticle and its potent effect on infectious agents and its therapeutic dimensions, the present study fully investigated the properties and performance of this metal-based nanoparticle.

摘要

传染病对人类生命的破坏作用以及抗生素耐药菌株的出现凸显了开发新的合适治疗策略的重要性,其中之一是使用金属作为治疗剂。铋纳米颗粒是著名的含金属药物的一个例子。铋基药物在伤口治疗中的疗效已得到证实。各种实验室研究已证实铋纳米颗粒的抗菌作用,包括对由……引起的溃疡的临床治疗。因此,考虑到这种纳米颗粒的性能及其对感染因子的强效作用及其治疗维度,本研究全面研究了这种金属基纳米颗粒的性质和性能。

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