Patané S, Virga T, Giannetto M, Luzza F, Oreto G, Arrigo F
Istituto Pluridisciplinare di Clinica Medica e Terapia Medica Generale e Speciale, Università di Messina.
G Ital Cardiol. 1987 Jul;17(7):605-8.
The efficacy of Propafenone to prevent exercise-induced ventricular arrhythmias (EIVA) has been studied in eleven patients affected by ischemic heart disease. None of the patients manifested any arrhythmia at rest, but ventricular arrhythmias occurred in every case during a treadmill test. EIVA disappeared after Propafenone in nine patients, while a reduction by 90% was achieved in the remaining two patients. A further treadmill test carried out five days after withdrawal of the drug induced again the same ventricular arrhythmias in all the patients. Thus, Propafenone appears effective to prevent EIVA in patients with ischemic heart disease.
已对11名患有缺血性心脏病的患者研究了普罗帕酮预防运动诱发室性心律失常（EIVA）的疗效。所有患者静息时均未出现任何心律失常，但在跑步机测试期间，每个病例均出现室性心律失常。9例患者服用普罗帕酮后EIVA消失，其余2例患者的室性心律失常减少了90%。停药五天后再次进行跑步机测试，所有患者再次出现相同的室性心律失常。因此，普罗帕酮似乎对预防缺血性心脏病患者的EIVA有效。
