Nephrology, Endocrinology and Vascular Medicine, Tohoku University Hospital, Sendai, Japan.
Nephrology, Endocrinology and Vascular Medicine, Tohoku University Hospital, Sendai, Japan
BMJ Case Rep. 2023 Feb 14;16(2):e254126. doi: 10.1136/bcr-2022-254126.
We report a case of eosinophilia and an allergic reaction that caused a cerebellar haemorrhage.An woman in her 80s presented with headache, dyspnoea and vomiting with severe hypotension soon after switching the dialysis membrane, and a CT scan revealed cerebellar haemorrhage. In the subsequent clinical course, the patient developed an allergic reaction to multiple membranes and required corticosteroids to continue haemodialysis (HD). Pre-existing eosinophilia is a risk factor for cerebral infarctions and dialysis membrane allergy, which is a common feature in patients undergoing HD. Membrane switching and corticosteroid therapy must be considered in case of multiple membrane allergies.
我们报告了一例嗜酸性粒细胞增多和过敏反应导致小脑出血的病例。一位 80 多岁的女性在更换透析膜后不久出现头痛、呼吸困难和呕吐,伴有严重低血压,CT 扫描显示小脑出血。在随后的临床过程中,患者对多种膜发生过敏反应,需要皮质类固醇继续进行血液透析 (HD)。 先前存在的嗜酸性粒细胞增多是脑梗死和透析膜过敏的危险因素,而后者是接受 HD 治疗的患者的常见特征。如果发生多种膜过敏,必须考虑更换膜和皮质类固醇治疗。